Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA. (Q46799727)

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9 January 2020

title

Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16282328%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

main subject

transmembrane transport

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transmembrane protein

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author

Melissa H Brown

4

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9 January 2020

author name string

Zhiqiang Xu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16282328%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Brendon A O'Rourke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16282328%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Ronald A Skurray

3

1 reference

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9 January 2020

language of work or name

English

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publication date

9 November 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16282328%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 January 2020

number of pages

8

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based on heuristic

inferred from page(s)

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16282328%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

281

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9 January 2020

issue

2

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9 January 2020

page(s)

792-799

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Phylogeny of multidrug transporters

9 January 2020

cites work

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Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity

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Inhibitors of branched-chain amino acid biosynthesis as potential antituberculosis agents

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Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations.

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Complete cysteine-scanning mutagenesis and site-directed chemical modification of the Tn10-encoded metal-tetracycline/H+ antiporter

21 January 2018

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19 In Vitro packaging of λ and cosmid DNA

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Efflux-mediated antiseptic resistance gene qacA from Staphylococcus aureus: common ancestry with tetracycline- and sugar-transport proteins

21 January 2018

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Determination of a transmembrane segment using cysteine-scanning mutants of transposon Tn10-encoded metal-tetracycline/H+ antiporter.

21 January 2018

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The transmembrane domains of the ABC multidrug transporter LmrA form a cytoplasmic exposed, aqueous chamber within the membrane

21 January 2018

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Structure and mechanism of the lactose permease of Escherichia coli

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The kamikaze approach to membrane transport

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Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein

21 January 2018

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Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr.

21 January 2018

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A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA.

21 January 2018

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Role of glycine residues in the structure and function of lactose permease, an Escherichia coli membrane transport protein

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Helix packing in polytopic membrane proteins: role of glycine in transmembrane helix association

21 January 2018

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The GxxxG motif: a framework for transmembrane helix-helix association

21 January 2018

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Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.

21 January 2018

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A transmembrane helix dimer: structure and implications

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The Calpha ---H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions

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Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs

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The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors

21 January 2018

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

21 January 2018

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Role of conserved residues in hydrophilic loop 8-9 of the lactose permease

21 January 2018

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Structural mechanisms of QacR induction and multidrug recognition

21 January 2018

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Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization

21 January 2018

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21 January 2018

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Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

21 January 2018

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21 January 2018

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Alteration of Substrate Specificity by Mutations at the His61Position in Predicted Transmembrane Domain 1 of Human MDR1/P-Glycoprotein†

21 January 2018

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