Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice. (Q46805060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199592%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Stimulation of calcineurin Aalpha activity attenuates muscle pathophysiology in mdx dystrophic mice (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199592%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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5

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1 January 2020

Nicole Stupka

1

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1 January 2020

author name string

Jonathan D Schertzer

2

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1 January 2020

Rhonda Bassel-Duby

3

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1 January 2020

Eric N Olson

4

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1 January 2020

publication date

16 January 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199592%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

1 January 2020

published in

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1 January 2020

volume

294

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issue

3

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page(s)

R983-92

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Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells

1 January 2020

cites work

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Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle

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Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1{alpha}, drives utrophin gene expression at the neuromuscular junction.

21 January 2018

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Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

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Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice

21 January 2018

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Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling

21 January 2018

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Shorter telomeres in dystrophic muscle consistent with extensive regeneration in young children

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Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers

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Improved contractile function of the mdx dystrophic mouse diaphragm muscle after insulin-like growth factor-I administration

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PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

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Interleukin-15 administration improves diaphragm muscle pathology and function in dystrophic mdx mice

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IL-4 acts as a myoblast recruitment factor during mammalian muscle growth

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Force and power output of diaphragm muscle strips from mdx and control mice after clenbuterol treatment

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A standardized method for the evaluation of respiratory muscle endurance in patients with Duchenne muscular dystrophy.

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Succinate dehydrogenase activities of fibers in the rat extensor digitorum longus, soleus, and cardiac muscles.

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Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo

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Cause of progression in Duchenne muscular dystrophy: impaired differentiation more probable than replicative aging

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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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Genetic disruption of calcineurin improves skeletal muscle pathology and cardiac disease in a mouse model of limb-girdle muscular dystrophy

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Static stretch promotes MEF2A nuclear translocation and expression of neonatal myosin heavy chain in C2C12 myocytes in a calcineurin- and p38-dependent manner.

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Cyclosporin A treatment upregulates Id1 and Smad3 expression and delays skeletal muscle regeneration.

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Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production

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Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways

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Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene

21 January 2018

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The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice.

21 January 2018

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Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice.

21 January 2018

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Calcineurin activation influences muscle phenotype in a muscle-specific fashion

21 January 2018

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Glycogen synthase kinase 3 suppresses myogenic differentiation through negative regulation of NFATc3.

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Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy.

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Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway

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p38 Mitogen-activated protein kinase-, calcium-calmodulin-dependent protein kinase-, and calcineurin-mediated signaling pathways transcriptionally regulate myogenin expression

21 January 2018

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Calcineurin Regulates Skeletal Muscle Metabolism via Coordinated Changes in Gene Expression

21 January 2018

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