T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro (Q46814728)

25 December 2017

title

T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro (English)

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25 December 2017

author

Allan Stensballe

4

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25 December 2017

Jesper Thorvald Troelsen

6

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25 December 2017

author name string

Rikke H Lewinsky

1

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25 December 2017

Tine G K Jensen

2

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25 December 2017

Jette Møller

3

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25 December 2017

Jørgen Olsen

5

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publication date

21 November 2005

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25 December 2017

published in

Human Molecular Genetics

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25 December 2017

volume

14

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25 December 2017

issue

24

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25 December 2017

page(s)

3945-3953

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25 December 2017

Adult-type hypolactasia and regulation of lactase expression

cites work

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https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Genetic signatures of strong recent positive selection at the lactase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Identification of a variant associated with adult-type hypolactasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

An upstream polymorphism associated with lactase persistence has increased enhancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

The HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1alpha-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase-isomaltase promoters are functionally related oligomeric molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

An enhancer activates the pig lactase phlorizin hydrolase promoter in intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Protein kinase A phosphorylates serine 267 in the homeodomain of engrailed-2 leading to decreased DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Subcellular localization of human glyceraldehyde-3-phosphate dehydrogenase is independent of its glycolytic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Novel interaction at the Cdx-2 binding sites of the lactase-phlorizin hydrolase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Rat lactase-phlorizin hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

T to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Yin Yang 1, Oct1, and NFAT-4 form repeating, cyclosporin-sensitive regulatory modules within the murine CD21 intronic control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Combinatorial control of gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI418

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI418

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25 December 2017

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25 December 2017