C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure (Q46815639)

25 December 2017

title

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure (English)

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25 December 2017

author name string

Jianhua Rao

1

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25 December 2017

Chuangyong Zhang

2

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25 December 2017

Ping Wang

3

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25 December 2017

Ling Lu

4

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25 December 2017

Xiaofeng Qian

5

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25 December 2017

Jianjie Qin

6

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25 December 2017

Xiongxiong Pan

7

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25 December 2017

Guoqiang Li

8

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25 December 2017

Xuehao Wang

9

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25 December 2017

Feng Zhang

10

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25 December 2017

language of work or name

English

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publication date

1 March 2015

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25 December 2017

published in

Biochemical Journal

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25 December 2017

volume

466

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25 December 2017

page(s)

369-378

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25 December 2017

issue

2

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25 December 2017

Endoplasmic reticulum stress in liver disease

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

21 January 2018

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

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Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells

21 January 2018

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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

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Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse

21 January 2018

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Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration

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Lipopolysaccharide preconditioning protects hepatocytes from ischemia/reperfusion injury (IRI) through inhibiting ATF4-CHOP pathway in mice

21 January 2018

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ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury

21 January 2018

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Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death

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21 January 2018

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Lethal effect of the anti-Fas antibody in mice

21 January 2018

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

21 January 2018

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Inhibition of glycogen synthase kinase 3β ameliorates D-GalN/LPS-induced liver injury by reducing endoplasmic reticulum stress-triggered apoptosis

21 January 2018

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Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding

21 January 2018

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CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.

21 January 2018

1 reference

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Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1042/BJ20140412

1 reference

25 December 2017

PubMed ID

25387528

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25 December 2017