Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells (Q46818407)

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scientific article published on 23 November 2005

Language	Label	Description	Also known as
English	Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells	scientific article published on 23 November 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

author name string

Defeng Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

Arthur I Cederbaum

2

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

publication date

23 November 2005

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

American Journal of Physiology - Gastrointestinal and Liver Physiology

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

290

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

4

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

G674-84

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer

1 reference

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S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

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Resolution of danazol-induced cholestasis with S-adenosylmethionine

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Biological Methylation: Selected Aspects

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Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations

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Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation

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21 January 2018

Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.

1 reference

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21 January 2018

Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates

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GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

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Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

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S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver

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Effect of S-adenosyl-L-methionine and dilinoleoylphosphatidylcholine on liver lipid composition and ethanol hepatotoxicity in isolated perfused rat liver.

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Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway

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Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation

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Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

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Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes

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Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver

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CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.

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21 January 2018

S-adenosylmethionine synthesis: molecular mechanisms and clinical implications

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Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats

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21 January 2018

5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

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Current concepts in the pathogenesis of alcoholic liver injury

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Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine

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Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1.

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21 January 2018

Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1.

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Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1.

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21 January 2018

Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria

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Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity

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21 January 2018

Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity

1 reference

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21 January 2018

Cytochrome P450IIE1: roles in nitrosamine metabolism and mechanisms of regulation

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The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastage

1 reference

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Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

1 reference

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21 January 2018

Identifiers

10.1152/AJPGI.00406.2005

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/16306132

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