Mutations in a Drosophila alpha2delta voltage-gated calcium channel subunit reveal a crucial synaptic function (Q46825820)

http://europepmc.org/abstract/MED/18171920

25 December 2017

title

Mutations in a Drosophila alpha2delta voltage-gated calcium channel subunit reveal a crucial synaptic function (English)

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http://europepmc.org/abstract/MED/18171920

25 December 2017

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Dion K Dickman

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

Peri T Kurshan

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

Thomas L Schwarz

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

language of work or name

English

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publication date

1 January 2008

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http://europepmc.org/abstract/MED/18171920

25 December 2017

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

volume

28

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

issue

1

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16 May 2020

page(s)

31-38

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

Calcium channelopathies in the central nervous system

16 May 2020

cites work

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12 December 2020

A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.

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RNA editing in the Drosophila DMCA1A calcium-channel alpha 1 subunit transcript.

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Identified motor terminals in Drosophila larvae show distinct differences in morphology and physiology.

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Genetic modifiers of the Drosophila NSF mutant, comatose, include a temperature-sensitive paralytic allele of the calcium channel alpha1-subunit gene, cacophony

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Ion channels and synaptic organization: analysis of the Drosophila genome

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A temperature-sensitive paralytic mutant defines a primary synaptic calcium channel in Drosophila.

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Reversibility of the Ca(2+) channel alpha(1)-beta subunit interaction.

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12 December 2020

Calcium channel alpha(2)delta subunits-structure and Gabapentin binding

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Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

1 reference

12 December 2020

Drosophila synaptotagmin I null mutants survive to early adulthood

1 reference

12 December 2020

The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function

1 reference

12 December 2020

Skeletal muscle L-type Ca(2+) current modulation in gamma1-deficient and wildtype murine myotubes by the gamma1 subunit and cAMP.

1 reference

12 December 2020

The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression

1 reference

12 December 2020

Synaptic calcium-channel function in Drosophila: analysis and transformation rescue of temperature-sensitive paralytic and lethal mutations of cacophony.

1 reference

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Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit

1 reference

12 December 2020

A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission

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The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation

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Effect of reduced impulse activity on the development of identified motor terminals in Drosophila larvae.

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Gamma subunit of voltage-activated calcium channels

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12 December 2020

Auxiliary subunits: essential components of the voltage-gated calcium channel complex.

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12 December 2020

Presynaptic N-type calcium channels regulate synaptic growth.

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12 December 2020

A further study of the statistical composition on the end-plate potential

1 reference

12 December 2020

Active zone localization of presynaptic calcium channels encoded by the cacophony locus of Drosophila.

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12 December 2020

Beta subunits of voltage-gated calcium channels

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12 December 2020

Calcium channel alpha2delta subunits: differential expression, function, and drug binding

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12 December 2020

Orchestrating development and function: retrograde BMP signaling in the Drosophila nervous system

1 reference

12 December 2020

Anticonvulsants and the relief of chronic pain: pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels

1 reference

12 December 2020

Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit.

1 reference

12 December 2020

Presynaptic calcium stores and synaptic transmission

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12 December 2020

Developmental consequences of neuromuscular junctions with reduced presynaptic calcium channel function.

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12 December 2020

External Ca2+ dependency of synaptic transmission in drosophila synaptotagmin I mutants

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12 December 2020

Molecular regulation of voltage-gated Ca2+ channels

1 reference

12 December 2020

A slowed classical pathway rather than kiss-and-run mediates endocytosis at synapses lacking synaptojanin and endophilin

1 reference

12 December 2020

Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila

1 reference

12 December 2020

Altered synaptic development and active zone spacing in endocytosis mutants

1 reference

12 December 2020

Kinetics of internalization and degradation of N-type voltage-gated calcium channels: role of the alpha2/delta subunit

1 reference

12 December 2020

Structural and functional abnormalities of retinal ribbon synapses due to Cacna2d4 mutation

1 reference

12 December 2020

Introduction on the use of the Drosophila embryonic/larval neuromuscular junction as a model system to study synapse development and function, and a brief summary of pathfinding and target recognition

1 reference

12 December 2020

Drosophila cacophony channels: a major mediator of neuronal Ca2+ currents and a trigger for K+ channel homeostatic regulation.

1 reference

12 December 2020

Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction

1 reference

12 December 2020

Co-operative action a calcium ions in transmitter release at the neuromuscular junction

1 reference

12 December 2020

A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans

1 reference

12 December 2020

Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission

1 reference

12 December 2020

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects.

1 reference

12 December 2020

The effect on synaptic physiology of synaptotagmin mutations in Drosophila

1 reference

12 December 2020

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

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12 December 2020

Analysis of genetic mosaics in developing and adult Drosophila tissues

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12 December 2020

The alpha 2/delta subunit of voltage sensitive Ca2+ channels is a single transmembrane extracellular protein which is involved in regulated secretion.

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12 December 2020

Structural and functional diversity of voltage-activated calcium channels.

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12 December 2020

Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction.

1 reference

12 December 2020

Genes affecting sensitivity to serotonin in Caenorhabditis elegans

1 reference

12 December 2020

Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse.

1 reference

12 December 2020

Extracellular interaction of the voltage-dependent Ca2+ channel alpha2delta and alpha1 subunits

1 reference

12 December 2020

Dissection of functional domains of the voltage-dependent Ca2+ channel alpha2delta subunit.

1 reference

12 December 2020

A mutation affecting dihydropyridine-sensitive current levels and activation kinetics in Drosophila muscle and mammalian heart calcium channels.

1 reference

12 December 2020

Courtship and visual defects of cacophony mutants reveal functional complexity of a calcium-channel alpha1 subunit in Drosophila

1 reference

12 December 2020

The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.

1 reference

12 December 2020

10.1523/JNEUROSCI.4498-07.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671140&resulttype=core&format=json

16 May 2020

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