Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits. (Q46832149)

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9 January 2020

title

Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits (English)

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9 January 2020

4

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author name string

M Sterba

1

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9 January 2020

T Simůnek

2

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Y Mazurová

3

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O Popelová

5

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J Kaplanova

6

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P Ponka

7

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V Gersl

8

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publication date

1 November 2005

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Human & Experimental Toxicology

9 January 2020

published in

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volume

24

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issue

11

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page(s)

581-589

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Chemistry and biology of eukaryotic iron metabolism

9 January 2020

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Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes

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Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells

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Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells

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The iron chelator pyridoxal isonicotinoyl hydrazone inhibits mitochondrial lipid peroxidation induced by Fe(II)-citrate

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Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits.

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The antioxidant effects of a novel iron chelator salicylaldehyde isonicotinoyl hydrazone in the prevention of H(2)O(2) injury in adult cardiomyocytes

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SIH--a novel lipophilic iron chelator--protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death.

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Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties

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Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

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Safety pharmacology: an essential interface of pharmacology and toxicology in the non-clinical assessment of new pharmaceuticals

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Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

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Cyclosporin A and vehicle toxicity in primary cultures of rabbit renal proximal tubule cells

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21 January 2018

Identifiers

DOI

1 reference

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9 January 2020

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