Detection of the moderately beneficial cognitive effects of low-dose treatment with haloperidol or clozapine in an animal model of the attentional impairments of schizophrenia (Q46840300)

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English	Detection of the moderately beneficial cognitive effects of low-dose treatment with haloperidol or clozapine in an animal model of the attentional impairments of schizophrenia	scientific article

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

Detection of the moderately beneficial cognitive effects of low-dose treatment with haloperidol or clozapine in an animal model of the attentional impairments of schizophrenia (English)

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

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Vicente Martinez

1

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

Martin Sarter

2

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

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19 December 2007

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

Neuropsychopharmacology

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

33

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

11

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

2635-2647

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301661

0 references

The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm

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Increased capacity and density of choline transporters situated in synaptic membranes of the right medial prefrontal cortex of attentional task-performing rats.

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Differential cortical acetylcholine release in rats performing a sustained attention task versus behavioral control tasks that do not explicitly tax attention

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Scopolamine induces disruption of latent inhibition which is prevented by antipsychotic drugs and an acetylcholinesterase inhibitor.

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Preattentional and attentional cognitive deficits as targets for treating schizophrenia

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Generalized and specific cognitive performance in clinical high-risk cohorts: a review highlighting potential vulnerability markers for psychosis

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Long-lasting psychotomimetic consequences of repeated low-dose amphetamine exposure in rhesus monkeys.

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Amphetamine sensitization of hallucinatory-like behaviors is dependent on prefrontal cortex in nonhuman primates

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Animal models of working memory: insights for targeting cognitive dysfunction in schizophrenia

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Amphetamine sensitization impairs cognition and reduces dopamine turnover in primate prefrontal cortex

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Differential effects of haloperidol and clozapine on attention.

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Cognitive sequelae of intravenous amphetamine self-administration in rats: evidence for selective effects on attentional performance

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Cortical cholinergic function and deficits in visual attentional performance in rats following 192 IgG-saporin-induced lesions of the medial prefrontal cortex

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Clozapine but not haloperidol treatment reverses sub-chronic phencyclidine-induced disruption of conditional discrimination performance.

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Improvement of prefrontal brain function in endogenous psychoses under atypical antipsychotic treatment.

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The amphetamine-induced sensitized state as a model of schizophrenia

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Sensitization to amphetamine, but not PCP, impairs attentional set shifting: reversal by a D1 receptor agonist injected into the medial prefrontal cortex

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A sensitizing regimen of amphetamine impairs visual attention in the 5-choice serial reaction time test: reversal by a D1 receptor agonist injected into the medial prefrontal cortex.

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Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia

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Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction

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Effort and cognition in schizophrenia patients.

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Dopamine-dependent interactions between limbic and prefrontal cortical plasticity in the nucleus accumbens: disruption by cocaine sensitization

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The neurocognitive effects of low-dose haloperidol: a two-year comparison with risperidone

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Increased distractibility in schizophrenic patients. Electrophysiologic and behavioral evidence.

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Predicting drug efficacy for cognitive deficits in schizophrenia

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Targeting information-processing deficit in schizophrenia: a novel approach to psychotherapeutic drug discovery

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Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial

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Progression of cellular adaptations in medial prefrontal and orbitofrontal cortex in response to repeated amphetamine

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Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum

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The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

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Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia

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Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient

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Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy

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Baseline neurocognitive deficits in the CATIE schizophrenia trial.

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Long-term neurocognitive effects of olanzapine or low-dose haloperidol in first-episode psychosis

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Mechanisms of action of atypical antipsychotic drugs: a critical analysis

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Augmented prefrontal acetylcholine release during challenged attentional performance

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Toward a neuro-cognitive animal model of the cognitive symptoms of schizophrenia: disruption of cortical cholinergic neurotransmission following repeated amphetamine exposure in attentional task-performing, but not non-performing, rats

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Increased dopamine transmission in schizophrenia: relationship to illness phases

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Time course of the antipsychotic effect and the underlying behavioral mechanisms.

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AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus.

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Effect sizes and p values: what should be reported and what should be replicated?

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10.1038/SJ.NPP.1301661

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18094665

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