The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose. (Q46845808)

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10 January 2020

title

The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose (English)

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10 January 2020

3

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10 January 2020

Wolfram Miekisch

6

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10 January 2020

Sebastian Klammt

4

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10 January 2020

author name string

Silke C Mueller

1

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10 January 2020

Jolanta Majcher-Peszynska

2

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10 January 2020

Ralf G Mundkowski

5

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10 January 2020

Hartwig Sievers

7

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10 January 2020

Steffen Bauer

8

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10 January 2020

Bruno Frank

9

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10 January 2020

Guenther Kundt

10

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10 January 2020

Bernd Drewelow

11

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10 January 2020

publication date

10 December 2005

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European Journal of Clinical Pharmacology

10 January 2020

published in

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10 January 2020

volume

62

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10 January 2020

issue

1

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10 January 2020

page(s)

29-36

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The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective

10 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00228-005-0061-3

Effect of St John's wort dose and preparations on the pharmacokinetics of digoxin

21 January 2018

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12 December 2020

Comparison of German St. John's wort products according to hyperforin and total hypericin content.

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12 December 2020

Pharmacokinetic interactions of drugs with St John's wort

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12 December 2020

Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.

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12 December 2020

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes

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12 December 2020

Drug interactions with St John's wort : mechanisms and clinical implications

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12 December 2020

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

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12 December 2020

Role of hyperforin in the pharmacological activities of St. John's Wort.

1 reference

12 December 2020

Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo

1 reference

12 December 2020

Pharmacokinetics and metabolism of oral midazolam in preterm infants

1 reference

12 December 2020

Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects

1 reference

12 December 2020

Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

1 reference

12 December 2020

St John's wort, a herbal antidepressant, activates the steroid X receptor.

1 reference

12 December 2020

In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs

1 reference

12 December 2020

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

1 reference

12 December 2020

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

1 reference

12 December 2020

Mechanism of action of St John's wort in depression : what is known?

1 reference

12 December 2020

St John's wort (Hypericum perforatum): drug interactions and clinical outcomes

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12 December 2020

The determination of total and unbound midazolam in human plasma. A comparison of high performance liquid chromatography, gas chromatography and gas chromatography/mass spectrometry

1 reference

12 December 2020

Analysis of the hypericin and pseudohypericin content of commercially available St John's Wort preparations

1 reference

12 December 2020

Determining hyperforin and hypericin content in eight brands of St. John's wort.

1 reference

12 December 2020