Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver (Q46848216)

25 December 2017

title

Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver (English)

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25 December 2017

author name string

Frank Dombrowski

series ordinal

1

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25 December 2017

Bruno Stieger

series ordinal

2

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25 December 2017

Ulrich Beuers

series ordinal

3

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25 December 2017

publication date

1 February 2006

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25 December 2017

published in

Laboratory Investigation

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25 December 2017

volume

86

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25 December 2017

issue

2

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25 December 2017

page(s)

166-174

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.3700371

exact match

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cites work

Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease

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Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases

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Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis

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Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver

21 January 2018

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Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets

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Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways

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The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

21 January 2018

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Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats

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Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase

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Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver

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The maintenance and generation of membrane polarity in hepatocytes

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Transcytosis: crossing cellular barriers

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Experimental LPS-induced cholestasis alters subcellular distribution and affects colocalization of Mrp2 and Bsep proteins: a quantitative colocalization study.

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Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

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Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

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Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes

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Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

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Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy

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Role of vesicle-mediated transport pathways in hepatocellular bile secretion

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Involvement of microtubules in the swelling-induced stimulation of transcellular taurocholate transport in perfused rat liver

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7 January 2021

Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver

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7 January 2021

Canalicular export pumps traffic with polymeric immunoglobulin A receptor on the same microtubule-associated vesicle in rat liver

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7 January 2021

The acinar location of the sodium-independent and the sodium-dependent component of taurocholate uptake. A histoautoradiographic study of rat liver

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7 January 2021

The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

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7 January 2021

Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes

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7 January 2021

10.1038/LABINVEST.3700371

Identifiers

DOI

1 reference

25 December 2017

1 reference

25 December 2017