Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis (Q46901983)

26 December 2017

title

Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis (English)

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26 December 2017

author

Matthias Gaestel

9

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Alexey Kotlyarov

4

object named as

Alexey Kotlyarov

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Anne Barbara Tietz

1

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Antje Malo

2

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Joachim Diebold

3

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Andreas Herbst

5

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Frank T Kolligs

6

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Barbara Brandt-Nedelev

7

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Walter Halangk

8

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Burkhard Göke

10

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Claus Schäfer

11

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publication date

19 January 2006

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26 December 2017

American Journal of Physiology - Gastrointestinal and Liver Physiology

published in

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volume

290

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issue

6

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page(s)

G1298-306

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Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

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Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice

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21 January 2018

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21 January 2018

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Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis

21 January 2018

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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

21 January 2018

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Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

21 January 2018

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MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

21 January 2018

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Distinct cellular functions of MK2.

21 January 2018

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Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis

21 January 2018

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21 January 2018

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MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

21 January 2018

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Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

21 January 2018

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Pathophysiology of pancreatitis. Role of cytokines and other mediators of inflammation

21 January 2018

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A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini

21 January 2018

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Pathophysiology of acute experimental pancreatitis: lessons from genetically engineered animal models and new molecular approaches

21 January 2018

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Hyperthermia induces multiple pancreatic heat shock proteins and protects against subsequent arginine-induced acute pancreatitis in rats

21 January 2018

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The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1152/AJPGI.00530.2005

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26 December 2017

PubMed ID

16423921

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26 December 2017