Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. (Q46907241)

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10 January 2020

title

Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans (English)

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1

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Miao Wang

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Tilo Grosser

6

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Muredach P. Reilly

7

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author name string

Emanuela Ricciotti

3

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Susanne Fries

4

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Ying Yu

5

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John A Lawson

8

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Garret A FitzGerald

9

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language of work or name

English

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publication date

8 November 2007

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Journal of Biological Chemistry

10 January 2020

published in

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volume

283

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issue

2

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page(s)

1179-1188

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Prostaglandin D synthase: structure and function

10 January 2020

cites work

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Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction

21 January 2018

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A controlled study of 9α,11β-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge

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Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid

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Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans

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Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

21 January 2018

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Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma

21 January 2018

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Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

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11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation

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Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9 alpha-11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2 alpha by bovine lung prostaglandin F synthase

21 January 2018

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Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects

21 January 2018

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Plasma 9alpha,11beta-PGF2, a PGD2 metabolite, as a sensitive marker of mast cell activation by allergen in bronchial asthma

21 January 2018

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Enzymatic preparation of carboxyl oxygen-18 labeled prostaglandin F2α and utility for quantitative mass spectrometry

21 January 2018

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Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation

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Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

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Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man

21 January 2018

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Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2.

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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice

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The lipocalin protein family: structure and function

21 January 2018

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9 alpha,11 beta-prostaglandin F2, a novel metabolite of prostaglandin D2 is a potent contractile agonist of human and guinea pig airways

21 January 2018

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Aspirin and decreased adult-onset asthma: randomized comparisons from the physicians' health study

21 January 2018

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Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

21 January 2018

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Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cells

21 January 2018

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Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity

21 January 2018

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Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

21 January 2018

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The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist

21 January 2018

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Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M706839200

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10 January 2020

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