Decreased glutathione levels potentiate the apoptotic efficacy of selenium: possible involvement of p38 and JNK MAPKs--in vitro studies (Q46909405)

26 December 2017

title

Decreased glutathione levels potentiate the apoptotic efficacy of selenium: possible involvement of p38 and JNK MAPKs--in vitro studies (English)

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26 December 2017

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Pavitra Ranawat

1

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26 December 2017

M P Bansal

series ordinal

2

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26 December 2017

publication date

8 November 2007

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26 December 2017

Molecular and Cellular Biochemistry

published in

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26 December 2017

volume

309

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26 December 2017

issue

1-2

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26 December 2017

page(s)

21-32

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26 December 2017

Programmed cell death in the reproductive system

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Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells

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Role of sphingomyelin-MAPKs pathway in heat-induced apoptosis.

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Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells

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Bcl-xL overexpression attenuates glutathione depletion in FL5.12 cells following interleukin-3 withdrawal

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Selenium and reproduction

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases

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Deterioration of plasma membrane is associated with activated caspases in human spermatozoa

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Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes

21 January 2018

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12 December 2020

ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts

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12 December 2020

Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells.

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12 December 2020

Expression of Bcl-2 increases intracellular glutathione by inhibiting methionine-dependent GSH efflux.

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12 December 2020

Bcl-2-mediated resistance to apoptosis is associated with glutathione-induced inhibition of AP24 activation of nuclear DNA fragmentation

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12 December 2020

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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12 December 2020

Suppressed NF-kB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-a induced apoptosis in human cancer cells

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12 December 2020

Mitochondrial reactive oxygen species in cell death signaling

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12 December 2020

Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance

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12 December 2020

Chemical depletion of glutathione in vivo

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12 December 2020

Germ cell suicide: new insights into apoptosis during spermatogenesis

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12 December 2020

Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes

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12 December 2020

Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

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12 December 2020

Evidence that lipopolysaccharide-induced cell death is mediated by accumulation of reactive oxygen species and activation of p38 in rat cortex and hippocampus.

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12 December 2020

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

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12 December 2020

A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells

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12 December 2020

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12 December 2020

Apoptosis-regulating proteins as targets for drug discovery

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12 December 2020

Glutathione: an overview of biosynthesis and modulation

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12 December 2020

Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases

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12 December 2020

MAPK and SRC-Kinases Control EGR-1 and NF-κB Inductions by Changes in Mechanical Environment in Osteoblasts

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12 December 2020

Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication

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12 December 2020

Effects of growth hormone on male reproductive functions

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12 December 2020

A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes

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12 December 2020

BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy

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12 December 2020

Caspase-3 and caspase-activated deoxyribonuclease are associated with testicular germ cell apoptosis resulting from reduced intratesticular testosterone

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12 December 2020

Depletion of glutathione by buthionine sulfoxine is cytotoxic for human neuroblastoma cell lines via apoptosis

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12 December 2020

Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target

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12 December 2020

Thiol-mediated redox regulation of neutrophil apoptosis

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12 December 2020

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

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12 December 2020

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

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12 December 2020

Apoptosis-based therapies and drug targets

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12 December 2020

Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2

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12 December 2020

NF-kappa B: ten years after

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12 December 2020

Bcl-2 and the regulation of programmed cell death

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12 December 2020

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

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12 December 2020

Spermatogonial stem cells

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12 December 2020

Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes

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12 December 2020

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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12 December 2020

In vitro techniques for the study of spermatogenesis

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12 December 2020

Biosynthesis and function of selenocysteine-containing enzymes.

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12 December 2020

Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis

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12 December 2020

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease

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12 December 2020

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

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12 December 2020

Suppression of nitric oxide-induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, bcl-2, and bax protein levels

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12 December 2020

Flupirtine increases the levels of glutathione and Bc1-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect

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12 December 2020

p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest

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12 December 2020

Role of reactive oxygen species in apoptosis: implications for cancer therapy.

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12 December 2020

A fluorometric method for determination of oxidized and reduced glutathione in tissues

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12 December 2020

Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity

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12 December 2020

The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology.

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12 December 2020

P21(Cip1/WAF1) expression in the mouse testis before and after X irradiation

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12 December 2020

Bcl-2 expression causes redistribution of glutathione to the nucleus

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12 December 2020

NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun

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12 December 2020

UV irradiation and heat shock mediate JNK activation via alternate pathways.

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12 December 2020

In-vitro effects of FSH and testosterone withdrawal on caspase activation and DNA fragmentation in different cell types of human seminiferous epithelium

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12 December 2020

Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes.

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12 December 2020

Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cells

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12 December 2020

Hormonal and genetic control of germ cell apoptosis in the testis

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12 December 2020

Participation of MAP kinase p38 and IkB kinase in chromium (VI)-induced NF-kB and AP-1 activation

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12 December 2020

Oxidative stress as a mediator of apoptosis

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12 December 2020

Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells

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12 December 2020

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

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12 December 2020

Oxidative stress is associated with increased apoptosis leading to spermatozoa DNA damage in patients with male factor infertility

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12 December 2020

Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells

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12 December 2020

Mouse islet cell lysis mediated by interleukin-1-induced Fas.

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12 December 2020

Caspases: potential targets for regulating cell death.

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12 December 2020

Caspase activity and apoptotic markers in ejaculated human sperm

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12 December 2020

Regulation of germ cell death in mammalian gonads.

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12 December 2020

beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase

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12 December 2020

Gene expression in the mouse retina: the effect of damaging light

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12 December 2020

Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism

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12 December 2020

p38 MAP kinase is involved in lipopolysaccharide-induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures

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12 December 2020

10.1007/S11010-007-9639-7

Identifiers

DOI

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26 December 2017

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26 December 2017