No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes in a Japanese population. (Q46929086)

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19 January 2020

title

No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes in a Japanese population (English)

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19 January 2020

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1

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19 January 2020

author name string

Hiroshi Inoue

2

1 reference

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19 January 2020

Yukiko Sakamoto

3

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19 January 2020

Kiyoshi Kunika

4

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19 January 2020

Toshihito Tanahashi

5

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19 January 2020

Naoto Nakamura

6

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19 January 2020

Toshikazu Yoshikawa

7

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19 January 2020

Natsuo Yasui

8

1 reference

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19 January 2020

Hiroshi Shiota

9

1 reference

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19 January 2020

Mitsuo Itakura

10

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19 January 2020

publication date

11 April 2006

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Journal of Human Genetics

19 January 2020

published in

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19 January 2020

volume

51

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19 January 2020

issue

6

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19 January 2020

page(s)

559-566

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https://scigraph.springernature.com/pub.10.1007/s10038-006-0399-0

19 January 2020

exact match

0 references

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12 December 2020

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

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Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

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12 December 2020

The K121Q polymorphism in the plasma cell membrane glycoprotein 1 gene predisposes to early myocardial infarction.

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Initial sequence of the chimpanzee genome and comparison with the human genome

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Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.

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Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study

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Earlier appearance of impaired insulin secretion than of visceral adiposity in the pathogenesis of NIDDM. 5-Year follow-up of initially nondiabetic Japanese-American men.

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12 December 2020

The K121Q Polymorphism of the ENPP1/PC-1 Gene Is Associated With Insulin Resistance/Atherogenic Phenotypes, Including Earlier Onset of Type 2 Diabetes and Myocardial Infarction

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12 December 2020

Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations

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12 December 2020

The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes

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12 December 2020

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

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12 December 2020

ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes

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12 December 2020

Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world.

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12 December 2020

The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth

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12 December 2020

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

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12 December 2020

Putting the genes for type II diabetes on the map

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12 December 2020

Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia

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12 December 2020

Membrane glycoprotein PC-1 and insulin resistance.

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12 December 2020

Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification

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12 December 2020

The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia

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12 December 2020

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance

1 reference

12 December 2020

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

1 reference

12 December 2020

Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs

1 reference

12 December 2020

The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance

1 reference

12 December 2020

Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.

1 reference

12 December 2020

The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121)

1 reference

12 December 2020

The impact of ethnicity on type 2 diabetes

1 reference

12 December 2020

Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1

1 reference

12 December 2020

K121Q PC‐1 Gene Polymorphism Is Not Associated with Insulin Resistance in a Spanish Population

1 reference

12 December 2020

Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance.

1 reference

12 December 2020

Role of PC-1 in the etiology of insulin resistance

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12 December 2020

Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit

1 reference

12 December 2020