Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase. (Q46930627)

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9 January 2020

title

Pre-steady-state kinetic studies establish entecavir 5'-triphosphate as a substrate for HIV-1 reverse transcriptase (English)

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9 January 2020

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4

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Raymond F Schinazi

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Robert F Siliciano

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Chloe L Thio

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1

Robert A Domaoal

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9 January 2020

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Kimberly L Rapp

8

object named as

Kimberly L Rapp

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9 January 2020

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author name string

Moira McMahon

2

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9 January 2020

Julian Tirado-Rives

5

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9 January 2020

Aleksander Obikhod

6

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9 January 2020

Mervi Detorio

7

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9 January 2020

Karen S Anderson

11

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9 January 2020

language of work or name

English

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publication date

25 October 2007

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Journal of Biological Chemistry

9 January 2020

published in

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volume

283

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issue

9

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9 January 2020

page(s)

5452-5459

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The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance

9 January 2020

cites work

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Fixed conformation nucleoside analogs effectively inhibit excision-proficient HIV-1 reverse transcriptases

21 January 2018

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Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance

21 January 2018

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Insights into the molecular mechanism of inhibition and drug resistance for HIV-1 RT with carbovir triphosphate

21 January 2018

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Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases

21 January 2018

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Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

21 January 2018

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Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1

21 January 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

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UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

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Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.

21 January 2018

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Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine

21 January 2018

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Mechanism and fidelity of HIV reverse transcriptase

21 January 2018

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12 December 2020

Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus

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12 December 2020

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12 December 2020

Hepatitis B virus reverse transcriptase and its many roles in hepadnaviral genomic replication

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12 December 2020

Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus

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12 December 2020

In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir.

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12 December 2020

Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations.

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12 December 2020

Treating opportunistic infections among HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America

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12 December 2020

Entecavir: a new nucleoside analogue for the treatment of chronic hepatitis B.

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12 December 2020