A "middle-out" approach to human pharmacokinetic predictions for OATP substrates using physiologically-based pharmacokinetic modeling (Q46942949)

26 December 2017

title

A "middle-out" approach to human pharmacokinetic predictions for OATP substrates using physiologically-based pharmacokinetic modeling (English)

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26 December 2017

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Rui Li

1

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26 December 2017

Hugh A Barton

2

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26 December 2017

Phillip D Yates

3

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26 December 2017

Avijit Ghosh

4

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26 December 2017

Angela C Wolford

5

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26 December 2017

Keith A Riccardi

6

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26 December 2017

Tristan S Maurer

7

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26 December 2017

publication date

10 April 2014

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26 December 2017

Journal of Pharmacokinetics and Pharmacodynamics

published in

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26 December 2017

volume

41

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26 December 2017

issue

3

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26 December 2017

page(s)

197-209

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26 December 2017

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

cites work

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Prediction of pharmacokinetic profile of valsartan in human based on in vitro uptake transport data

21 January 2018

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Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans

21 January 2018

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Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans

21 January 2018

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Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data

21 January 2018

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21 January 2018

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An integrated strategy for prediction uncertainty analysis

21 January 2018

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Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

21 January 2018

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Influence of nonspecific brain and plasma binding on CNS exposure: implications for rational drug discovery

21 January 2018

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A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed-effects models.

21 January 2018

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Prediction of pharmacokinetic profile of valsartan in humans based on in vitro uptake-transport data

21 January 2018

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Mechanistic modeling to predict the transporter- and enzyme-mediated drug-drug interactions of repaglinide

21 January 2018

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A mechanistic framework for in vitro-in vivo extrapolation of liver membrane transporters: prediction of drug-drug interaction between rosuvastatin and cyclosporine

21 January 2018

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Ethnic variability in the plasma exposures of OATP1B1 substrates such as HMG-CoA reductase inhibitors: a kinetic consideration of its mechanism

21 January 2018

1 reference

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Impact of OATP transporters on pharmacokinetics

21 January 2018

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Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin

21 January 2018

1 reference

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Combining the 'bottom up' and 'top down' approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24718648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A novel strategy for physiologically based predictions of human pharmacokinetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24718648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10928-014-9357-1

1 reference

26 December 2017

release_vpvck6ibqbbunkgrgj6lcye2ki

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vpvck6ibqbbunkgrgj6lcye2ki

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

26 December 2017