PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats (Q46963094)

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scientific article published on 24 February 2006

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English	PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats	scientific article published on 24 February 2006

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scholarly article

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats (English)

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

0 references

6

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

author name string

Xueying Zhao

1

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

Jeffrey E Quigley

2

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

Jianghe Yuan

3

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

Mong-Heng Wang

4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

Yiqing Zhou

5

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

publication date

24 February 2006

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

American Journal of Physiology Heart and Circulatory Physiology

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

290

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26 December 2017

http://europepmc.org/abstract/MED/16501022

H2187-95

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

6

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Endothelial dysfunction: a marker of atherosclerotic risk

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

PPAR agonists amplify iNOS expression while inhibiting NF-kappaB: implications for mesangial cell activation by cytokines.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Effects of micronized fenofibrate versus atorvastatin in the treatment of dyslipidaemic patients with low plasma HDL-cholesterol levels: a 12-week randomized trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Cytochrome P450 2C is an EDHF synthase in coronary arteries

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Impaired dilation of skeletal muscle microvessels to reduced oxygen tension in diabetic obese Zucker rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Impaired NO-dependent dilation of skeletal muscle arterioles in hypertensive diabetic obese Zucker rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Fenofibrate improves insulin sensitivity in connection with intramuscular lipid content, muscle fatty acid-binding protein, and beta-oxidation in skeletal muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Altered renal microvascular response in Zucker obese rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Eicosanoid regulation of the renal vasculature

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

The effect of fenofibrate treatment on endothelium-dependent relaxation induced by oxidative modified low density lipoprotein from hyperlipidemic patients

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Mechanisms underlying the attenuation of endothelium-dependent vasodilatation in the mesenteric arterial bed of the streptozotocin-induced diabetic rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Fenofibrate lowers adiposity and corrects metabolic abnormalities, but only partially restores endothelial function in dietary obese rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Prostacyclin signaling in the kidney: implications for health and disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)alpha-mediated cardiovascular effects

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Effect of fenofibrate on brachial artery flow-mediated dilatation in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

The role of the cytochrome P450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: a review

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Fenofibrate inhibits angiogenesis in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Comparison of effects of diabetes mellitus on an EDHF-dependent and an EDHF-independent artery

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Reactive oxygen species and vascular signal transduction mechanisms

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00937.2005

21 January 2018

Identifiers

10.1152/AJPHEART.00937.2005

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/16501022

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