An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene (Q46984270)

27 December 2017

title

An interleukin-2 signal relieves BSAP (Pax5)-mediated repression of the immunoglobulin J chain gene (English)

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27 December 2017

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J L Rinkenberger

1

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27 December 2017

J J Wallin

series ordinal

2

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27 December 2017

K W Johnson

series ordinal

3

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27 December 2017

M E Koshland

series ordinal

4

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27 December 2017

language of work or name

English

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publication date

1 October 1996

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27 December 2017

published in

Immunity

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27 December 2017

volume

5

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27 December 2017

page(s)

377-386

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27 December 2017

issue

4

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27 December 2017

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

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A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor

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Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements

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Molecular mechanisms regulating CD19, CD20 and CD22 gene expression

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The coming of age of the immunoglobulin J chain

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The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

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Changes in J chain and mu chain RNA expression as a function of B cell differentiation

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A promoter element that exerts positive and negative control of the interleukin 2-responsive J-chain gene

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Interleukin 2- and interleukin 5-induced changes in the binding of regulatory factors to the J-chain gene promoter

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Accessibility of the promoter sequence in the J-chain gene is regulated by chromatin changes during B-cell differentiation

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Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription

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BSAP: a key regulator of B-cell development and differentiation

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Polymer IgM assembly and secretion in lymphoid and nonlymphoid cell lines: evidence that J chain is required for pentamer IgM synthesis

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A pre-B- and B cell-specific DNA-binding protein, EBB-1, which binds to the promoter of the VpreB1 gene.

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Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA.

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

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Blimp-1 overcomes the block in IgM secretion in lipopolysaccharide/anti-mu F(ab')2-co-stimulated B lymphocytes.

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NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation

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7 January 2021

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Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

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7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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7 January 2021

The B cell-specific transcription factor BSAP regulates B cell proliferation

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7 January 2021

10.1016/S1074-7613(00)80263-0

Identifiers

DOI

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27 December 2017

PubMed ID

8885870

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27 December 2017