Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma (Q46989511)

27 December 2017

title

Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma (English)

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27 December 2017

author name string

Emily H Smith

series ordinal

1

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27 December 2017

Ralf Janknecht

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2

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27 December 2017

L James Maher

series ordinal

3

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27 December 2017

publication date

19 September 2007

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27 December 2017

published in

Human Molecular Genetics

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27 December 2017

volume

16

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27 December 2017

page(s)

3136-3148

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27 December 2017

issue

24

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27 December 2017

Phenotypic dichotomy in mitochondrial complex II genetic disorders.

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

The ubiquinone-binding site of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase is a source of superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A Chinese hamster mutant cell line with a defect in the integral membrane protein CII-3 of complex II of the mitochondrial electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

JmjC-domain-containing proteins and histone demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Identification of histone demethylases in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Mitochondrial protein oxidation in yeast mutants lacking manganese-(MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD): evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Increased spontaneous DNA damage in Cu/Zn superoxide dismutase (SOD1) deficient Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Null mutants of Saccharomyces cerevisiae Cu,Zn superoxide dismutase: characterization and spontaneous mutation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Reduction in frataxin causes progressive accumulation of mitochondrial damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Regulation of yAP-1 nuclear localization in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Histone demethylation by a family of JmjC domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A role for mitochondrial enzymes in inherited neoplasia and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Hypoxia increases heparanase-dependent tumor cell invasion, which can be inhibited by antiheparanase antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Mitochondrial defects in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Somatic mutations of the mitochondrial genome in human colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

An Alu-mediated partial SDHC deletion causes familial and sporadic paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Reactive oxygen species in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Antioxidants protect the yeast Saccharomyces cerevisiae against hypertonic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

A tale of histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Histone methylation in transcriptional control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Set2-catalyzed methylation of histone H3 represses basal expression of GAL4 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Transcriptional activators in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Dynamic Regulation of Histone Lysine Methylation by Demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

10 Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Accelerated nuclei preparation and methods for analysis of histone modifications in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Automated spectrophotometric analysis of mitochondrial respiratory chain complex enzyme activities in cultured skin fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Analysis of the ERK-stimulated ETS transcription factor ER81.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Diversity within the JMJD2 histone demethylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM275

21 January 2018

Identifiers

DOI

10.1093/HMG/DDM275

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27 December 2017

PubMed ID

17884808

1 reference

27 December 2017