Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. (Q47035972)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28459430%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28459430%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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GOA release 2020-03-11

cardiolipin binding

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GOA release 2020-03-11

Gasdermin E

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GOA release 2020-03-11

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4

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19 March 2020

author name string

Yupeng Wang

1

1 reference

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19 March 2020

Wenqing Gao

2

1 reference

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19 March 2020

Xuyan Shi

3

1 reference

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19 March 2020

Wang Liu

5

1 reference

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19 March 2020

Huabin He

6

1 reference

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19 March 2020

Kun Wang

7

1 reference

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19 March 2020

Feng Shao

8

1 reference

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19 March 2020

language of work or name

English

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publication date

1 May 2017

1 reference

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19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28459430%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

547

1 reference

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19 March 2020

issue

7661

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19 March 2020

page(s)

99-103

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https://scigraph.springernature.com/pub.10.1038/nature22393

19 March 2020

exact match

0 references

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Inflammasomes: mechanism of action, role in disease, and therapeutics

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Pyroptotic cell death defends against intracellular pathogens

21 January 2018

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SnapShot: The Noncanonical Inflammasome

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

21 January 2018

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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

21 January 2018

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Pore-forming activity and structural autoinhibition of the gasdermin family

21 January 2018

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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

21 January 2018

1 reference

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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

21 January 2018

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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

21 January 2018

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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

21 January 2018

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Nonsyndromic hearing impairment is associated with a mutation in DFNA5

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Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy

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The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage

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Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer

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DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cells

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Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

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DFNA5, a gene involved in hearing loss and cancer: a review

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Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

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A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment.

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Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

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The expression and regulation of DFNA5 in human hepatocellular carcinoma DFNA5 in hepatocellular carcinoma.

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Hypomethylating agent combination strategies in myelodysplastic syndromes: hopes and shortcomings

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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

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Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

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A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.

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Inflammatory caspases are innate immune receptors for intracellular LPS.

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7 January 2021

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An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals

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Methylation of the DFNA5 gene is frequently detected in colorectal cancer

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PubMed

https://pubmed.ncbi.nlm.nih.gov/28459430