SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development (Q47068882)

4 January 2018

title

SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development (English)

1 reference

4 January 2018

Protein kinase domain-containing protein;Serine/threonine-protein kinase spk-1 CELE_B0464.5

main subject

Caenorhabditis elegans

0 references

1 reference

Putative splicing factor, arginine/serine-rich 3 CELE_Y111B2A.18

GOA release 2020-03-11

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GOA release 2020-03-11

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Kuroyanagi H

1

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4 January 2018

Kimura T

2

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4 January 2018

Wada K

3

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4 January 2018

Hisamoto N

4

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4 January 2018

Matsumoto K

5

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4 January 2018

Hagiwara M

6

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4 January 2018

publication date

1 December 2000

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4 January 2018

Mechanisms of Development

published in

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4 January 2018

volume

99

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4 January 2018

page(s)

51-64

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4 January 2018

issue

1-2

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4 January 2018

The genome sequence of Drosophila melanogaster

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glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

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Transcript analysis of glp-1 and lin-12, homologous genes required for cell interactions during development of C. elegans

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FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

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Molecular cloning and sequencing of ama-1, the gene encoding the largest subunit of Caenorhabditis elegans RNA polymerase II.

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Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

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Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

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In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase

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Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo.

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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A serine kinase regulates intracellular localization of splicing factors in the cell cycle

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Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

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Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans

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Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

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The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

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Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

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The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability.

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RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

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The type 2C Ser/Thr phosphatase PP2Cgamma is a pre-mRNA splicing factor

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Characterization and comparison of four serine- and arginine-rich (SR) protein kinases

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Functional properties of the unc-64 gene encoding a Caenorhabditis elegans syntaxin.

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cdc2 kinase-mediated phosphorylation of splicing factor SF2/ASF.

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Onset of C. elegans gastrulation is blocked by inhibition of embryonic transcription with an RNA polymerase antisense RNA.

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7 January 2021

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

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7 January 2021

Conservation in budding yeast of a kinase specific for SR splicing factors

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7 January 2021

RNAi in C. elegans: soaking in the genome sequence

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SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

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Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors

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7 January 2021

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

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7 January 2021

Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

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7 January 2021

SR proteins: a conserved family of pre-mRNA splicing factors

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7 January 2021

Operons as a common form of chromosomal organization in C. elegans

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7 January 2021

10.1016/S0925-4773(00)00477-9

Identifiers

DOI

1 reference

4 January 2018

PubMed ID

11091073

1 reference

4 January 2018