Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis (Q47073937)

5 January 2018

title

Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis (English)

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5 January 2018

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Brent W Bisgrove

1

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5 January 2018

Brian S Snarr

series ordinal

2

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5 January 2018

Anoush Emrazian

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3

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5 January 2018

H Joseph Yost

series ordinal

4

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5 January 2018

language of work or name

English

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publication date

7 October 2005

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5 January 2018

published in

Developmental Biology

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5 January 2018

volume

287

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5 January 2018

issue

2

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5 January 2018

page(s)

274-288

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5 January 2018

A Human Syndrome Caused by Immotile Cilia

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A molecular pathway leading to endoderm formation in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

casanova plays an early and essential role in endoderm formation in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Axis development and early asymmetry in mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Classification of left-right patterning defects in zebrafish, mice, and humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Genetics of human laterality disorders: insights from vertebrate model systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The ins and outs of polycystin-2 as a calcium release channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Identification and characterization of polycystin-2, the PKD2 gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mechanisms of left-right determination in vertebrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A cluster of noninvoluting endocytic cells at the margin of the zebrafish blastoderm marks the site of embryonic shield formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Conserved function for embryonic nodal cilia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Axonemal dynein intermediate-chain gene (DNAI1) mutations result in situs inversus and primary ciliary dyskinesia (Kartagener syndrome)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Hedgehog signalling in the mouse requires intraflagellar transport proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Genetics and pathogenesis of polycystic kidney disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Polycystin-2 is an intracellular calcium release channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A motility in the eukaryotic flagellum unrelated to flagellar beating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Molecular complexes formed with polycystins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A molecular pathway determining left-right asymmetry in chick embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The zebrafishnodal-related genesouthpawis required for visceral and diencephalic left-right asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Two populations of node monocilia initiate left-right asymmetry in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Effective targeted gene 'knockdown' in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Determination of left–right patterning of the mouse embryo by artificial nodal flow

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

fork head domain genes in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Abnormal nodal flow precedes situs inversus in iv and inv mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Loss-of-function mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The ion channel polycystin-2 is required for left-right axis determination in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Chromosome 4 localization of a second gene for autosomal dominant polycystic kidney disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Bending the MDCK cell primary cilium increases intracellular calcium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Removal of the MDCK cell primary cilium abolishes flow sensing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

PKD1 interacts with PKD2 through a probable coiled-coil domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

cyclops encodes a nodal-related factor involved in midline signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Xenopus embryos regulate the nuclear localization of XMyoD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Morphogenesis of the murine node and notochordal plate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Somatic inactivation of Pkd2 results in polycystic kidney disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Polycystin-1 activates and stabilizes the polycystin-2 channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Distinct roles of transcription factors EGL-46 and DAF-19 in specifying the functionality of a polycystin-expressing sensory neuron necessary for C. elegans male vulva location behavior

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

The guts of endoderm formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.08.047

10.1016/J.YDBIO.2005.08.047

7 January 2021

Identifiers

DOI

1 reference

5 January 2018

1 reference

5 January 2018