Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria (Q47100582)

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scientific article published on 4 December 2015

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English	Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria	scientific article published on 4 December 2015

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scholarly article

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Europe PubMed Central

8 January 2018

http://europepmc.org/abstract/PMC/5724392

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria (English)

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http://europepmc.org/abstract/PMC/5724392

transcranial Doppler

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inferred from title

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object named as

Peng Wei

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Theodosia A. Kalfa

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Theodosia A Kalfa

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Janet L Kwiatkowski

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object named as

Janet L Kwiatkowski

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object named as

Russell E Ware

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author name string

William H Schultz

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R Clark Brown

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Banu Aygun

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Sharada Sarnaik

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Isaac Odame

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Beng Fuh

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Alex George

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William Owen

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Lori Luchtman-Jones

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Zora R Rogers

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Lee Hilliard

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Cynthia Gauger

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Connie Piccone

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Margaret T Lee

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Sherron Jackson

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Scott T Miller

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Carla Roberts

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Matthew M Heeney

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Stephen Nelson

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Hamayun Imran

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Kerri Nottage

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Ofelia Alvarez

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Melissa Rhodes

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Alexis A Thompson

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Jennifer A Rothman

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Kathleen J Helton

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Donna Roberts

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Jamie Coleman

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Melanie J Bonner

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Abdullah Kutlar

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Niren Patel

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John Wood

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Linda Piller

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Judy Luden

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Nicole A Mortier

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Susan E Stuber

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Naomi L C Luban

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Alan R Cohen

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Sara Pressel

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Robert J Adams

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language of work or name

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publication date

4 December 2015

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number of pages

10

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661-670

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Optimizing hydroxyurea therapy for sickle cell anemia

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23 May 2018

Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea.

1 reference

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23 May 2018

Therapeutic phlebotomy is safe in children with sickle cell anaemia and can be effective treatment for transfusional iron overload

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23 May 2018

Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members

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23 May 2018

Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia

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23 May 2018

Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial

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23 May 2018

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia

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23 May 2018

Developmental function in toddlers with sickle cell anemia

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23 May 2018

Stroke With Transfusions Changing to Hydroxyurea (SWiTCH): a phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overload

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23 May 2018

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).

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23 May 2018

Genetic predictors for stroke in children with sickle cell anemia

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23 May 2018

Effect of transfusion therapy on transcranial Doppler ultrasonography velocities in children with sickle cell disease

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23 May 2018

Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease

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23 May 2018

How I use hydroxyurea to treat young patients with sickle cell anemia

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23 May 2018

Hydroxyurea therapy lowers transcranial Doppler flow velocities in children with sickle cell anemia

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23 May 2018

Intra-individual variation in blood flow velocities in cerebral arteries of children with sickle cell disease

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23 May 2018

Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.

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23 May 2018

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

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23 May 2018

The use of transcranial ultrasonography to predict stroke in sickle cell disease.

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16 June 2018

Physician attitude, awareness, and knowledge regarding guidelines for transcranial Doppler screening in sickle cell disease

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15 August 2018

Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities.

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15 August 2018

Long-term results using hydroxyurea/phlebotomy for reducing secondary stroke risk in children with sickle cell anemia and iron overload

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15 August 2018

Impact of early transcranial Doppler screening and intensive therapy on cerebral vasculopathy outcome in a newborn sickle cell anemia cohort

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A critical assessment of transcranial doppler screening rates in a large pediatric sickle cell center: opportunities to improve healthcare quality

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15 August 2018

Hydroxyurea for children with sickle cell disease

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15 August 2018

Hydroxyurea for sickle cell disease in children and for prevention of cerebrovascular events: the Belgian experience.

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15 August 2018

Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomy

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15 August 2018

Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease

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7 January 2021

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Computations for group sequential boundaries using the Lan-DeMets spending function method

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7 January 2021

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Cerebrovascular accidents in sickle cell disease: rates and risk factors

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https://pubmed.ncbi.nlm.nih.gov/26670617

12 December 2020

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Identifiers

10.1016/S0140-6736(15)01041-7

1 reference

Europe PubMed Central

8 January 2018

http://europepmc.org/abstract/PMC/5724392

1 reference

Europe PubMed Central

8 January 2018

http://europepmc.org/abstract/PMC/5724392

1 reference

Europe PubMed Central

8 January 2018

http://europepmc.org/abstract/PMC/5724392

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