Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase (Q47185013)

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scientific article published on 14 April 2015

Language	Label	Description	Also known as
English	Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase	scientific article published on 14 April 2015

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase (English)

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

author name string

H Nakamura

1

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

J X Wang

2

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

E P Balskus

3

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

publication date

14 April 2015

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

Chemical Science

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

6

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

7

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

3816-3822

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

Roles of type II thioesterases and their application for secondary metabolite yield improvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5707447

23 May 2018

Cylindrocyclophane biosynthesis involves functionalization of an unactivated carbon center

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5707447

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Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation

1 reference

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Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor

1 reference

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23 May 2018

Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity

1 reference

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Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor

1 reference

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Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis

1 reference

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PKS and NRPS release mechanisms

1 reference

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Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures

1 reference

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Acyltransferase mediated polyketide release from a fungal megasynthase

1 reference

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Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis

1 reference

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23 May 2018

Structure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne Biosynthesis

1 reference

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23 May 2018

Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway

1 reference

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23 May 2018

Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin

1 reference

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A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

1 reference

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Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis.

1 reference

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From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes

1 reference

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Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining

1 reference

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Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase

1 reference

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Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

1 reference

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23 May 2018

The chalcone synthase superfamily of type III polyketide synthases

1 reference

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23 May 2018

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

1 reference

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23 May 2018

Polyketide biosynthesis: a millennium review

1 reference

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23 May 2018

Type I polyketide biosynthesis in bacteria (part B).

1 reference

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23 May 2018

Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis).

1 reference

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Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.

1 reference

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Biosynthesis of the 4-methyloxazoline-containing nonribosomal peptides, JBIR-34 and -35, in Streptomyces sp. Sp080513GE-23.

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An unusual thioesterase promotes isochromanone ring formation in ajudazol biosynthesis

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14 August 2018

A PLP-dependent polyketide chain releasing mechanism in the biosynthesis of mycotoxin fumonisins in Fusarium verticillioides

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Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis.

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Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin.

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Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated.

1 reference

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Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin

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1 reference

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1 reference

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Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae.

1 reference

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4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

1 reference

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1 reference

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Identification of NanE as the thioesterase for polyether chain release in nanchangmycin biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29218151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29218151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of 3-methylorcinaldehyde synthase (MOS) in Acremonium strictum: first observation of a reductive release mechanism during polyketide biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29218151

12 December 2020

based on heuristic

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Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29218151

12 December 2020

based on heuristic

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Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29218151

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Fatty acyl-AMP ligase involvement in the production of alkylresorcylic acid by a Myxococcus xanthus type III polyketide synthase

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Identifiers

10.1039/C4SC03132F

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 January 2018

http://europepmc.org/abstract/PMC/5707447

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