Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. (Q47228271)

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8 April 2020

title

Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis (English)

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8 April 2020

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6

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8 April 2020

Xabier Buqué

3

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8 April 2020

Uxia Fernandez

5

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8 April 2020

Miguel López

11

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8 April 2020

Guadalupe Sabio

12

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8 April 2020

Ruben Nogueiras

15

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8 April 2020

author name string

Begoña Porteiro

1

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8 April 2020

Marcos F Fondevila

2

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8 April 2020

Maria J Gonzalez-Rellan

4

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8 April 2020

Daniel Beiroa

7

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8 April 2020

Ana Senra

8

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Rosalia Gallego

9

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8 April 2020

Johan Fernø

10

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8 April 2020

Carlos Dieguez

13

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Patricia Aspichueta

14

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8 April 2020

publication date

15 December 2017

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8 April 2020

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8 April 2020

volume

8

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8 April 2020

page(s)

132-143

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Hepatic p63 regulates steatosis via IKKβ/ER stress

8 April 2020

cites work

1 reference

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Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis

30 June 2018

1 reference

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Pharmacological and Genetic Manipulation of p53 in Brown Fat at Adult But Not Embryonic Stages Regulates Thermogenesis and Body Weight in Male Mice

30 June 2018

1 reference

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p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration.

30 June 2018

1 reference

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Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells

30 June 2018

1 reference

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Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

30 June 2018

1 reference

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Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation

30 June 2018

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Metabolic regulation by p53 family members.

30 June 2018

1 reference

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Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease

30 June 2018

1 reference

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Regulation of lipid metabolism by p53 - fighting two villains with one sword.

30 June 2018

1 reference

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Lipid metabolism in cancer

30 June 2018

1 reference

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ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

30 June 2018

1 reference

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p53, a novel regulator of lipid metabolism pathways.

30 June 2018

1 reference

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Effects of quercetin on the bioavailability of doxorubicin in rats: role of CYP3A4 and P-gp inhibition by quercetin

30 June 2018

1 reference

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p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

30 June 2018

1 reference

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Doxorubicin cardiomyopathy

30 June 2018

1 reference

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THE METABOLISM OF TUMORS IN THE BODY

30 June 2018

1 reference

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Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.

30 June 2018

1 reference

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p53: guardian of the genome and policeman of the oncogenes.

30 June 2018

1 reference

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p53 in health and disease

30 June 2018

1 reference

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Troponin: the biomarker of choice for the detection of cardiac injury

30 June 2018

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p53 involvement in the pathogenesis of fatty liver disease.

30 June 2018

1 reference

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p53 Activation in Adipocytes of Obese Mice

30 June 2018

1 reference

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Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone-induced liver damage through inflammation and endoplasmic reticulum stress.

30 June 2018

1 reference

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p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.

14 August 2018

1 reference

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Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression.

14 August 2018

1 reference

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Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways

14 August 2018

1 reference

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Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29290620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLMET.2017.12.005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29290620%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29290620%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference