Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial. (Q47243953)

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7 April 2020

title

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial (English)

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Hans-Christian von Büdingen

15

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3

Bruce A Cree

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Stephen L Hauser

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1

Ari J Green

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2

Jeffrey M Gelfand

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Carolyn Bevan

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Alyssa Zhu

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Jonah R Chan

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Justin Inman

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Michael Devereux

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Aya Abounasr

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author name string

W John Boscardin

5

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Feng Mei

6

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Sam Arnow

8

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Hiroko Nobuta

11

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Matt Friessen

13

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Roy Gerona

14

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Roland G Henry

16

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language of work or name

English

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publication date

10 October 2017

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7 April 2020

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volume

390

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issue

10111

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page(s)

2481-2489

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Multiple sclerosis--the plaque and its pathogenesis

7 April 2020

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Cells of the oligodendroglial lineage, myelination, and remyelination

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Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo

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Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis

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Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells

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Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

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Electron microscopic features of multiple sclerosis lesions

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Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences

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Ions, energy and axonal injury: towards a molecular neurology of multiple sclerosis

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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

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A regenerative approach to the treatment of multiple sclerosis

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Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

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7 January 2021

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice.

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7 January 2021

Clemastine rescues behavioral changes and enhances remyelination in the cuprizone mouse model of demyelination

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7 January 2021

Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish.

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7 January 2021

Visual evoked response in diagnosis of multiple sclerosis

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Screening for cognitive impairment in multiple sclerosis using the Symbol digit Modalities Test.

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7 January 2021

The assessment of fatigue: a practical guide for clinicians and researchers.

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7 January 2021

Psychosocial correlates of fatigue in multiple sclerosis

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7 January 2021

Evoked potential changes in clinically definite multiple sclerosis: a two year follow up study

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7 January 2021

Outcome measures for trials of remyelinating agents in multiple sclerosis: retrospective longitudinal analysis of visual evoked potential latency

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7 January 2021

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7 January 2021

Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration

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7 January 2021

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7 January 2021

Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay

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Identifiers

DOI

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7 April 2020

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