The macrophage-specific serum marker, soluble CD163, is increased in obesity and reduced after dietary-induced weight loss (Q47246931)

12 January 2018

title

The macrophage-specific serum marker, soluble CD163, is increased in obesity and reduced after dietary-induced weight loss (English)

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author name string

Karen Fjeldborg

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Tore Christiansen

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Marianne Bennetzen

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Holger J Møller

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Bjørn Richelsen

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Bjørn Richelsen

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publication date

2 July 2013

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published in

Obesity

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volume

21

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issue

12

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page(s)

2437-2443

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Identification and characterization of metabolically benign obesity in humans

cites work

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Inflammation: the link between insulin resistance, obesity and diabetes

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Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue

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Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.

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Obesity is associated with macrophage accumulation in adipose tissue

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Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects.

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CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response.

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Tumor necrosis factor α-converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163.

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Changes in fat mass correlate with changes in soluble sCD163, a marker of mature macrophages, in patients with CKD.

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Adiponectin downregulates CD163 whose cellular and soluble forms are elevated in obesity.

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Relationship between monocyte/macrophage activation marker soluble CD163 and insulin resistance in obese and normal-weight subjects

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Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals

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Comparable reduction of the visceral adipose tissue depot after a diet-induced weight loss with or without aerobic exercise in obese subjects: a 12-week randomized intervention study.

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

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The usefulness of circulating adipokine levels for the assessment of obesity-related health problems

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Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

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Weight loss due to a very low calorie diet differentially affects insulin sensitivity and interleukin-6 serum levels in nondiabetic obese human subjects

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The link between abdominal obesity and the metabolic syndrome

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Soluble CD163: a biomarker linking macrophages and insulin resistance

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Identifiers

DOI

10.1002/OBY.20376

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