SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. (Q47292718)

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17 November 2019

title

SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling (English)

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17 November 2019

2

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17 November 2019

author name string

Akiko Kimura

1

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17 November 2019

Yumiko Matsumura

3

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17 November 2019

Hiroyuki Mori

4

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17 November 2019

Ryuichi Mashima

5

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17 November 2019

Mine Harada

6

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17 November 2019

Kenneth R Chien

7

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17 November 2019

Hideo Yasukawa

8

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17 November 2019

Akihiko Yoshimura

9

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17 November 2019

language of work or name

English

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publication date

29 December 2003

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Journal of Biological Chemistry

17 November 2019

published in

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17 November 2019

volume

279

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17 November 2019

page(s)

6905-6910

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17 November 2019

issue

8

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Negative regulation of cytokine signaling pathways

17 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

SOCS proteins: negative regulators of cytokine signaling

21 January 2018

1 reference

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

21 January 2018

1 reference

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SOCS3 is essential in the regulation of fetal liver erythropoiesis

21 January 2018

1 reference

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SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

21 January 2018

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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

21 January 2018

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Direct binding of Shc, Grb2, SHP-2 and p40 to the murine granulocyte colony-stimulating factor receptor

21 January 2018

1 reference

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Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

21 January 2018

1 reference

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Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

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Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

21 January 2018

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Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

21 January 2018

1 reference

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Flow cytometry-based phagocytosis assay for sensitive detection of opsonic activity of pneumococcal capsular polysaccharide antibodies in human sera

21 January 2018

1 reference

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Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line

21 January 2018

1 reference

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Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia

21 January 2018

1 reference

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Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300496200

21 January 2018

Identifiers

DOI

10.1074/JBC.C300496200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14699146%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference