Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function (Q47364974)

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scientific article published in November 2003

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English	Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function	scientific article published in November 2003

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scholarly article

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function (English)

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

author name string

J S Shumsky

1

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

C A Tobias

2

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

M Tumolo

3

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

W D Long

4

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

S F Giszter

5

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

M Murray

6

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

language of work or name

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publication date

1 November 2003

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

Experimental Neurology

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

184

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

1

1 reference

Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

114-130

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

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Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of function differ after spinal cord injury in newborn and adult rats.

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Probable corticospinal tract control of spinal cord plasticity in the rat.

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Mechanical and thermal allodynia in chronic central pain following spinal cord injury

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Chronic central pain after spinal cord injury

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Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins.

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Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors

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trkC expression in the injured rat spinal cord

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Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord

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Expression of beta-calcitonin gene-related peptide in axotomized rubrospinal neurons and the effect of brain derived neurotrophic factor.

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Transmitters involved in antinociception in the spinal cord

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Altered respiratory motor drive after spinal cord injury: supraspinal and bilateral effects of a unilateral lesion.

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Effect of cervical spinal cord hemisection and hemidiaphragm paralysis on arterial blood gases, pH, and respiratory rate in the adult rat

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Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

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Transplants of adrenal medullary chromaffin cells reduce forelimb and hindlimb allodynia in a rodent model of chronic central pain after spinal cord hemisection injury

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Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat.

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Engraftment of serotonergic precursors enhances locomotor function and attenuates chronic central pain behavior following spinal hemisection injury in the rat.

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A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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Motor-sensory cortex-corticospinal system and developing locomotion and placing in rats

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7 January 2021

Degeneration and sprouting of identified descending supraspinal axons after contusive spinal cord injury in the rat.

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7 January 2021

Vestibular stimulation affects medium latency postural muscle responses.

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Chronically injured supraspinal neurons exhibit only modest axonal dieback in response to a cervical hemisection lesion

1 reference

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7 January 2021

Transplantation of fetal spinal cord tissue into the chronically injured adult rat spinal cord

1 reference

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7 January 2021

Survival of chronically-injured neurons can be prolonged by treatment with neurotrophic factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

7 January 2021

Effects of red nucleus ablation and exogenous neurotrophin-3 on corticospinal axon terminal distribution in the adult rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

7 January 2021

Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

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Transplantation of genetically modified fibroblasts expressing BDNF in adult rats with a subtotal hemisection improves specific motor and sensory functions

1 reference

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trkA, trkB, and trkC messenger RNA expression by bulbospinal cells of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

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Increased innervation of rat preganglionic sympathetic neurons by substance P containing nerve fibers in response to spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

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Sprouting of primary afferent fibers after spinal cord transection in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

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Recovery of function after spinal cord hemisection in newborn and adult rats: differential effects on reflex and locomotor function

1 reference

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Reaxotomy of chronically injured rubrospinal neurons results in only modest cell loss

1 reference

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Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.

1 reference

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Grafts of BDNF-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy.

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Functional redundancy of ventral spinal locomotor pathways.

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Cervical motoneuron topography reflects the proximodistal organization of muscles and movements of the rat forelimb: a retrograde carbocyanine dye analysis

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The effects of NGF and sensory nerve stimulation on collateral sprouting and gene expression in adult sensory neurons.

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Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A.

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Efficient testing of motor function in spinal cord injured rats.

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Strain and model differences in behavioral outcomes after spinal cord injury in rat

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Fetal transplants alter the development of function after spinal cord transection in newborn rats

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Restitution of function and collateral sprouting in the cat spinal cord: the partially hemisected animal

1 reference

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BDNF abolishes the survival effect of NT-3 in axotomized Clarke neurons of adult rats

1 reference

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Survival effects of BDNF and NT-3 on axotomized rubrospinal neurons depend on the temporal pattern of neurotrophin administration

1 reference

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Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord

1 reference

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Plasticity of dorsal root and descending serotoninergic projections after partial deafferentation of the adult rat spinal cord

1 reference

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Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats

1 reference

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Neurotrophin-3-Mediated Regeneration and Recovery of Proprioception Following Dorsal Rhizotomy

1 reference

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Functional regeneration of sensory axons into the adult spinal cord.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

7 January 2021

Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy.

1 reference

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The recovery of 5-HT immunoreactivity in lumbosacral spinal cord and locomotor function after thoracic hemisection

1 reference

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Neurotrophins reduce degeneration of injured ascending sensory and corticospinal motor axons in adult rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4886%2803%2900398-4

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Ex vivo MR determined apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to express BDNF.

1 reference

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Critical interval for rescue of axotomized neurons by transplants

1 reference

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Neurotrophins and hyperalgesia.

1 reference

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7 January 2021

Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration

1 reference

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7 January 2021

NT-3 gene delivery elicits growth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection.

1 reference

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7 January 2021

Regeneration and sprouting of chronically injured corticospinal tract fibers in adult rats promoted by NT-3 and the mAb IN-1, which neutralizes myelin-associated neurite growth inhibitors.

1 reference

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Plasticity of spinal systems after unilateral lumbosacral dorsal rhizotomy in the adult rat

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Normal development and the effects of early rhizotomy on spinal systems in the rat

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Compensatory locomotor adjustments of rats with cervical or thoracic spinal cord hemisections

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Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury

1 reference

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Confocal microscopic analysis reveals sprouting of primary afferent fibres in rat dorsal horn after spinal cord injury

1 reference

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Excitotoxic spinal cord injury: behavioral and morphological characteristics of a central pain model

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Contributions of injured and intact afferents to neuropathic pain in an experimental rat model.

1 reference

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Proliferation of SP- and 5HT-containing terminals in lamina II of rat spinal cord following dorsal rhizotomy: quantitative EM-immunocytochemical studies

1 reference

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Plasticity of complex terminals in lamina II in partially deafferented spinal cord: the cat spared root preparation

1 reference

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7 January 2021

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10.1016/S0014-4886(03)00398-4

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

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https://api.fatcat.wiki/v0/release/4gk42abznbfw5megcp4xoippfm

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Europe PubMed Central

14 January 2018

http://europepmc.org/abstract/MED/14637085

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