Quantitative structure-activity relationships (QSARs) for substrates of human cytochromes P450 CYP2 family enzymes (Q47373215)

15 January 2018

title

Quantitative structure-activity relationships (QSARs) for substrates of human cytochromes P450 CYP2 family enzymes (English)

1 reference

15 January 2018

author name string

David F V Lewis

series ordinal

1

1 reference

15 January 2018

publication date

1 February 2004

1 reference

15 January 2018

published in

Toxicology in Vitro

1 reference

15 January 2018

volume

18

1 reference

15 January 2018

issue

1

1 reference

15 January 2018

page(s)

89-97

1 reference

15 January 2018

Competitive CYP2C9 inhibitors: enzyme inhibition studies, protein homology modeling, and three-dimensional quantitative structure-activity relationship analysis

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Cytochromes P450 and metabolism of xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

A unified theory of enzyme kinetics based upon the systematic analysis of the variations of k(cat), K(M), and k(cat)/K(M) and the relevant DeltaG(0 not equal) values-possible implications in chemotherapy and biotechnology.

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

The role of CYP2B6 in human xenobiotic metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Homology modelling of human CYP2 family enzymes based on the CYP2C5 crystal structure

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Quantitative structure-activity relationships (QSARs) within the cytochrome P450 system: QSARs describing substrate binding, inhibition and induction of P450s

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Molecular Binding Interactions: Their Estimation and Rationalization in QSARs in Terms of Theoretically Derived Parameters.

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Quantitative structure-activity relationships (QSARs) within series of inhibitors for mammalian cytochromes P450 (CYPs)

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Factors influencing rates and clearance in P450-mediated reactions: QSARs for substrates of the xenobiotic-metabolizing hepatic microsomal P450s.

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Quantitative structure-activity relationships (QSARs) within substrates of human cytochromes P450 involved in drug metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Structure-activity relationship for human cytochrome P450 substrates and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Cytochrome P450 and the individuality of species

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

CYP2A6: a human coumarin 7-hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modeling

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0887-2333%2803%2900134-6

7 January 2021

10.1016/S0887-2333(03)00134-6

Identifiers

DOI

1 reference

15 January 2018

release_cmhqvhhuf5fy5nlw6zp6uqfmu4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cmhqvhhuf5fy5nlw6zp6uqfmu4

24 November 2022

mapped directly with Wikidata item

1 reference

15 January 2018