Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma (Q47375627)

15 January 2018

title

Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma (English)

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15 January 2018

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4

Domenico Coppola

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15 January 2018

author name string

Ardeshir Hakam

series ordinal

1

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15 January 2018

Quan Fang

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2

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15 January 2018

Richard Karl

series ordinal

3

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15 January 2018

publication date

1 October 2003

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15 January 2018

Digestive Diseases and Sciences

published in

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15 January 2018

volume

48

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issue

10

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15 January 2018

page(s)

1972-1978

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Survival statistics gone awry: pancreatic cancer, a case in point

cites work

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Three-dimensional structure of the tyrosine kinase c-Src

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Increased tumorigenicity in the human pancreatic cell line MIA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-beta type RII receptor

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c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

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IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

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Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers

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The when and how of Src regulation

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Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

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Elevated c-Src protein expression is an early event in colonic neoplasia

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Insulin-like growth factor I and transforming growth factor alpha as autocrine growth factors in human pancreatic cancer cell growth

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Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis

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TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor

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High-affinity monomeric 67-kd laminin receptors and prognosis in pancreatic endocrine tumours

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Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

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Cancer of the pancreas. Palliative operation, Whipple procedure, or total pancreatectomy?

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Glycoprotein tyrosine phosphorylation in Rous sarcoma virus-transformed chicken embryo fibroblasts

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Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells.

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Controlling IGF-receptor function: a possible strategy for tumor therapy

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A possible novel src-related tyrosine kinase in cancer cells of LEC rats that develop hepatocellular carcinoma

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Cross-classification and survival characteristics of 5,000 cases of cancer of the pancreas.

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

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Identifiers

DOI

10.1023/A:1026122421369

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15 January 2018

Dimensions Publication ID

1019974556

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15 January 2018