Pneumococcal whole-cell and protein-based vaccines: changing the paradigm (Q47410739)

15 January 2018

title

Pneumococcal whole-cell and protein-based vaccines: changing the paradigm (English)

1 reference

15 January 2018

Pneumococcal conjugate vaccines

main subject

clinical trial

0 references

0 references

author name string

Michael E Pichichero

series ordinal

1

1 reference

15 January 2018

language of work or name

English

0 references

publication date

1 December 2017

1 reference

15 January 2018

Expert Review of Vaccines

published in

1 reference

15 January 2018

volume

16

1 reference

15 January 2018

issue

12

1 reference

15 January 2018

page(s)

1181-1190

1 reference

15 January 2018

Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.

cites work

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Which pneumococcal serogroups cause the most invasive disease: implications for conjugate vaccine formulation and use, part I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Rapid pneumococcal evolution in response to clinical interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Pneumococcal disease caused by serotype 19A: review of the literature and implications for future vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Predicting the impact of new pneumococcal conjugate vaccines: serotype composition is not enough

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Population genomics of post-vaccine changes in pneumococcal epidemiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

The rise and fall of pneumococcal serotypes carried in the PCV era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Status of research and development of pediatric vaccines for Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Early impact of sequential introduction of 7-valent and 13-valent pneumococcal conjugate vaccine on IPD in Israeli children <5 years: an active prospective nationwide surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Insight Into Resistance Phenotypes of Emergent Non 13-valent Pneumococcal Conjugate Vaccine Type Pneumococci Isolated From Invasive Disease After 13-valent Pneumococcal Conjugate Vaccine Implementation in France

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Serotypes, antimicrobial susceptibility, and molecular epidemiology of invasive and non-invasive Streptococcus pneumoniae isolates in paediatric patients after the introduction of 13-valent conjugate vaccine in a nationwide surveillance study conduc

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease in children in the USA: a matched case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Safety, tolerability and immunogenicity of 15-valent pneumococcal conjugate vaccine in toddlers previously vaccinated with 7-valent pneumococcal conjugate vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: randomised, controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Randomized controlled study of the safety and immunogenicity of pneumococcal vaccine formulations containing PhtD and detoxified pneumolysin with alum or adjuvant system AS02V in elderly adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Reactogenicity, safety and immunogenicity of a protein-based pneumococcal vaccine in Gambian children aged 2-4 years: A phase II randomized study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Safety and immunogenicity of an investigational vaccine containing two common pneumococcal proteins in toddlers: a phase II randomized clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Safety and immunogenicity of the pneumococcal pneumolysin derivative PlyD1 in a single-antigen protein vaccine candidate in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Safety and immunogenicity of a trivalent recombinant PcpA, PhtD, and PlyD1 pneumococcal protein vaccine in adults, toddlers, and infants: A phase I randomized controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Rationale and prospects for novel pneumococcal vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Next generation protein based Streptococcus pneumoniae vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

The pneumococcus: why a commensal misbehaves

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Protection against Streptococcus pneumoniae Invasive Pathogenesis by a Protein-Based Vaccine Is Achieved by Suppression of Nasopharyngeal Bacterial Density during Influenza A Virus Coinfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

The incidence of invasive pneumococcal serotype 3 disease in the Danish population is not reduced by PCV-13 vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Serotype-specific effectiveness and correlates of protection for the 13-valent pneumococcal conjugate vaccine: a postlicensure indirect cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Decreased Carriage and Genetic Shifts in the Streptococcus pneumoniae Population After Changing the Seven-valent to the Thirteen-valent Pneumococcal Vaccine in Norway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Proteomic comparisons of opaque and transparent variants of Streptococcus pneumoniae by two dimensional-differential gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Differential protein expression in phenotypic variants of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Requirement for capsule in colonization by Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Protective contributions against invasive Streptococcus pneumoniae pneumonia of antibody and Th17-cell responses to nasopharyngeal colonisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Serum antibody responses to pneumococcal colonization in the first 2 years of life: results from an SE Asian longitudinal cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Modeling pneumococcal nasopharyngeal acquisition as a function of anticapsular serum antibody concentrations after pneumococcal conjugate vaccine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Streptococcus pneumoniae colonisation: the key to pneumococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Pneumococcal carriage in children in The Netherlands: a molecular epidemiological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Antibody response to Streptococcus pneumoniae proteins PhtD, LytB, PcpA, PhtE and Ply after nasopharyngeal colonization and acute otitis media in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Higher levels of mucosal antibody to pneumococcal vaccine candidate proteins are associated with reduced acute otitis media caused by Streptococcus pneumoniae in young children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Reduced IL-17A Secretion Is Associated with High Levels of Pneumococcal Nasopharyngeal Carriage in Fijian Children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Toll-like receptor 2-dependent protection against pneumococcal carriage by immunization with lipidated pneumococcal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Broad antibody and T cell reactivity induced by a pneumococcal whole-cell vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

What to do about pertussis vaccines? Linking what we know about pertussis vaccine effectiveness, immunology and disease transmission to create a better vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Pertussis: acellular, whole-cell, new vaccines, what to choose?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Interleukin-17A mediates acquired immunity to pneumococcal colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

T(H)17-based vaccine design for prevention of Streptococcus pneumoniae colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Distinct effects on diversifying selection by two mechanisms of immunity against Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Nasopharyngeal colonization of Gambian infants by Staphylococcus aureus and Streptococcus pneumoniae before the introduction of pneumococcal conjugate vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Impaired serotype-specific immune function following pneumococcal vaccination in infants with prior carriage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Characterization of Th17 responses to Streptococcus pneumoniae in humans: comparisons between adults and children in a developed and a developing country

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Ten-Year Study of the Stringently Defined Otitis-prone Child in Rochester, NY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Differential impact of respiratory syncytial virus and parainfluenza virus on the frequency of acute otitis media is explained by lower adaptive and innate immune responses in otitis-prone children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Synchrony in serum antibody response to conserved proteins of Streptococcus pneumoniae in young children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Serum antibody response to five Streptococcus pneumoniae proteins during acute otitis media in otitis-prone and non-otitis-prone children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Lower nasopharyngeal epithelial cell repair and diminished innate inflammation responses contribute to the onset of acute otitis media in otitis-prone children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Regulating vaccines at the FDA: development and licensure of Zika vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian infants: a longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Early acquisition and high nasopharyngeal co-colonisation by Streptococcus pneumoniae and three respiratory pathogens amongst Gambian new-borns and infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Ten-Year Study of Acute Otitis Media in Rochester, NY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Reduced memory CD4+ T-cell generation in the circulation of young children may contribute to the otitis-prone condition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Reduced serum IgG responses to pneumococcal antigens in otitis-prone children may be due to poor memory B-cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Nonprotective responses to pediatric vaccines occur in children who are otitis prone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Vaccine nanoparticles for protection against HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Analysis of novel meningococcal vaccine formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Monophosphoryl Lipid A Enhances Efficacy of a Francisella tularensis LVS-Catanionic Nanoparticle Subunit Vaccine against F. tularensis Schu S4 Challenge by Augmenting both Humoral and Cellular Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1393335

Differences in intestinal humoral immunity between healthy volunteers from UK and Bangladesh

21 January 2018

1 reference

12 December 2020

Longitudinal study on pneumococcal carriage during the first year of life in Bangladesh

1 reference

12 December 2020

Serotype distribution of Streptococcus pneumoniae infections among preschool children in the United States, 1978-1994: implications for development of a conjugate vaccine

1 reference

12 December 2020

Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae

1 reference

12 December 2020

Relationship between colonial morphology and adherence of Streptococcus pneumoniae

1 reference

12 December 2020

Safety and immunogenicity of pneumococcal protein vaccine candidates: monovalent choline-binding protein A (PcpA) vaccine and bivalent PcpA-pneumococcal histidine triad protein D vaccine

1 reference

12 December 2020

Whooping cough: the current scene

1 reference

12 December 2020

Epidemiological evidence for serotype-independent acquired immunity to pneumococcal carriage

1 reference

12 December 2020

Safety, tolerability, and immunogenicity of 15-valent pneumococcal conjugate vaccine in healthy adults

1 reference

12 December 2020

Pertussis vaccines: WHO position paper

1 reference

12 December 2020

Immunity to the respiratory pathogen Bordetella pertussis.

1 reference

12 December 2020

Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice

1 reference

12 December 2020

Vaccines for the unvaccinated: protecting the herd

1 reference

12 December 2020

Otitis-prone Children Have Immunologic Deficiencies in Naturally Acquired Nasopharyngeal Mucosal Antibody Response after Streptococcus pneumoniae Colonization

1 reference

12 December 2020

Acellular vaccines for preventing whooping cough in children

1 reference

12 December 2020

Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization

1 reference

12 December 2020

Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice

1 reference

12 December 2020

10.1080/14760584.2017.1393335

Identifiers

DOI

1 reference

15 January 2018

PMC publication ID

6277969

0 references

1 reference

15 January 2018