Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes (Q47421825)

16 January 2018

title

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes (English)

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https://api.crossref.org/works/10.1016/S1097-2765(03)00395-2

25 March 2024

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https://api.crossref.org/works/10.1016/S1097-2765(03)00395-2

25 March 2024

6

Eric C Holland

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16 January 2018

Julia R Vinagolu-Baur

1

object named as

Vinagolu K. Rajasekhar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580340

25 March 2024

author name string

Agnes Viale

2

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16 January 2018

Martin Wiedmann

4

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16 January 2018

Xiaoyi Hu

5

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16 January 2018

Nicholas D. Socci

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580340

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language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14580340

25 March 2024

publication date

1 October 2003

1 reference

16 January 2018

full work available at URL

http://www.cell.com/article/S1097276503003952/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14580340

https://api.elsevier.com/content/article/PII:S1097276503003952?httpAccept=text/xml

25 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(03)00395-2

https://api.elsevier.com/content/article/PII:S1097276503003952?httpAccept=text/plain

25 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(03)00395-2

25 March 2024

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16 January 2018

volume

12

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16 January 2018

issue

4

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16 January 2018

page(s)

889-901

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16 January 2018

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

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S6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells

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Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection

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Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

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PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

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RNA logic in time and space

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Decreased proliferation of human melanoma cell lines caused by antisense RNA against translation factor eIF-4A1.

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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

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Regulation of translation initiation by FRAP/mTOR

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Proliferation of human malignant astrocytomas is dependent on Ras activation.

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Gliomagenesis: genetic alterations and mouse models

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A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

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7 January 2021

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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7 January 2021

Mechanisms of resistance to rapamycins

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

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7 January 2021

Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

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The WHO classification of tumors of the nervous system

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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7 January 2021

The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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Ras mediates translation initiation factor 4E-induced malignant transformation

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Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency

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The ribosome filter hypothesis

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7 January 2021

Control of eukaryotic protein synthesis by upstream open reading frames in the 5'-untranslated region of an mRNA

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7 January 2021

Translation control: bridging the gap between genomics and proteomics?

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Highly purified pea chloroplast RNA polymerase transcribes both rRNA and mRNA genes

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Decreasing the level of translation initiation factor 4E with antisense RNA causes reversal of ras-mediated transformation and tumorigenesis of cloned rat embryo fibroblasts.

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A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

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Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.

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Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays

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7 January 2021

Translation initiation and its deregulation during tumorigenesis

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7 January 2021

The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

25 March 2024

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25 March 2024

Identifiers

1 reference

16 January 2018

1 reference

16 January 2018