FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction (Q47565787)

4 February 2018

title

FM19G11 favors spinal cord injury regeneration and stem cell self-renewal by mitochondrial uncoupling and glucose metabolism induction (English)

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4 February 2018

main subject

stem cell self-renewal

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4

Miodrag Stojkovic

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4 February 2018

author name string

Francisco Javier Rodríguez-Jimnez

1

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Ana Alastrue-Agudo

2

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Slaven Erceg

3

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4 February 2018

Victoria Moreno-Manzano

5

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publication date

1 October 2012

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4 February 2018

published in

Stem Cells

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4 February 2018

volume

30

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issue

10

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page(s)

2221-2233

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Activated spinal cord ependymal stem cells rescue neurological function.

cites work

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The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

21 January 2018

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Mitochondria determine the differentiation potential of cardiac mesoangioblasts.

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Energy metabolism in nuclear reprogramming

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Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

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Temporal characterization of mitochondrial bioenergetics after spinal cord injury.

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Ectopic UCP1 gene expression in HepG2 cells affects ATP production

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A fundamental system of cellular energy homeostasis regulated by PGC-1alpha

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Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise

21 January 2018

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Mitochondrial uncoupling as a therapeutic target following neuronal injury

21 January 2018

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Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector

21 January 2018

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Differential effects of the mitochondrial uncoupling agent, 2,4-dinitrophenol, or the nitroxide antioxidant, Tempol, on synaptic or nonsynaptic mitochondria after spinal cord injury

21 January 2018

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The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord

21 January 2018

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The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

21 January 2018

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Activation and signaling by the AMP-activated protein kinase in endothelial cells

21 January 2018

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Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells

21 January 2018

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AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.

21 January 2018

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Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells

21 January 2018

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FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status.

21 January 2018

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Human pluripotent stem cells decouple respiration from energy production

21 January 2018

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UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

21 January 2018

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Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

21 January 2018

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Transplanted oligodendrocytes and motoneuron progenitors generated from human embryonic stem cells promote locomotor recovery after spinal cord transection.

21 January 2018

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FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

21 January 2018

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Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners

21 January 2018

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Recent advances in glucokinase activators for the treatment of type 2 diabetes

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Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

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Stat3 activation is limiting for reprogramming to ground state pluripotency.

21 January 2018

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Targeting mammalian target of rapamycin (mTOR) for health and diseases.

21 January 2018

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Muscle cell depolarization induces a gain in surface GLUT4 via reduced endocytosis independently of AMPK.

21 January 2018

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A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

21 January 2018

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Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

21 January 2018

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No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

21 January 2018

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AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues

21 January 2018

1 reference

Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death

21 January 2018

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Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells

21 January 2018

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Resveratrol stimulates AMP kinase activity in neurons

21 January 2018

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Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

21 January 2018

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Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury

21 January 2018

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Mitochondrial uncoupling as a potential therapeutic target in acute central nervous system injury

21 January 2018

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Reexpression of vimentin in differentiated neuroblastoma cells enhances elongation of axonal neurites

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1189

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4 February 2018

release_zpq5ggbihjhr5ck46yprfalmui

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/zpq5ggbihjhr5ck46yprfalmui

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22865656

1 reference

4 February 2018