Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses (Q47583435)

4 February 2018

title

Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses (English)

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4 February 2018

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J Mühlisch

1

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4 February 2018

T Bajanowski

2

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4 February 2018

C H Rickert

3

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W Roggendorf

4

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4 February 2018

G Würthwein

5

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H Jürgens

6

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M C Frühwald

7

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publication date

6 January 2007

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4 February 2018

Journal of Neuro-Oncology

published in

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4 February 2018

volume

83

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4 February 2018

issue

1

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4 February 2018

page(s)

17-29

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4 February 2018

https://scigraph.springernature.com/pub.10.1007/s11060-006-9309-8

exact match

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cites work

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Dependence of transcriptional repression on CpG methylation density

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Stability of patch methylation and its impact in regions of transcriptional initiation and elongation

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Inactive chromatin spreads from a focus of methylation

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Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

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Aberrant methylation of p14ARF gene correlates with poor survival in osteosarcoma.

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Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility.

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Transcriptional inactivation of the tissue inhibitor of metalloproteinase-3 gene by dna hypermethylation of the 5'-CpG island in human gastric cancer cell lines.

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Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

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Peak height variations in automated sequencing of PCR products using Taq dye-terminator chemistry

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Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.

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Expression of E-cadherin in human mast cell line HMC-1.

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Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

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Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer.

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Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis.

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Infiltrating leukocytes confound the detection of E-cadherin promoter methylation in tumors

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Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma.

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Metastatic medulloblastoma--therapeutic success through molecular target identification?

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DNA methylation analysis by MethyLight technology

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De novo quantitative bisulfite sequencing using the pyrosequencing technology.

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A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels

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Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines

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Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon

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p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

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Aberrant hypermethylation of the major breakpoint cluster region in 17p11.2 in medulloblastomas but not supratentorial PNETs.

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Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood

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O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort

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DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project

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Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

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Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas.

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Genetics of pediatric central nervous system tumors

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Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

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MGMT gene silencing and benefit from temozolomide in glioblastoma

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12 December 2020

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

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12 December 2020

MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma

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DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia

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12 December 2020

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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Initial sequencing and analysis of the human genome

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12 December 2020

10.1007/S11060-006-9309-8

Identifiers

DOI

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4 February 2018

PubMed ID

17206475

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4 February 2018