Molecular dynamics study of peptide segments of the BH3 domain of the proapoptotic proteins Bak, Bax, Bid and Hrk bound to the Bcl-xL and Bcl-2 proteins. (Q47604133)

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English	Molecular dynamics study of peptide segments of the BH3 domain of the proapoptotic proteins Bak, Bax, Bid and Hrk bound to the Bcl-xL and Bcl-2 proteins.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Molecular dynamics study of peptide segments of the BH3 domain of the proapoptotic proteins Bak, Bax, Bid and Hrk bound to the Bcl-xL and Bcl-2 proteins (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Juan Jesús Pérez

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Jaime Rubio-Martínez

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Marta Pinto

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

publication date

1 January 2004

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Journal of Computer - Aided Molecular Design

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

18

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

13-22

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

The receptor for the cytotoxic ligand TRAIL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2 family: regulators of cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death and anti-death: tumour resistance to apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: killer proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis by death factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-based therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the interacting cell death regulators CED-9 and CED-4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 and the regulation of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death in the immune system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo electroporetic transfer of bcl-2 antisense oligonucleotide inhibits the development of hepatocellular carcinoma in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of protein–protein interactions by mutagenesis: direct versus indirect effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15143800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:JCAM.0000022559.72848.1C

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

DBLP publication ID

journals/jcamd/PintoPR04

1 reference

DBLP Dataset 2021-01-02

28 January 2021

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15143800%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

ResearchGate publication ID

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