Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. (Q47608130)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29046435%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

title

Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys (English)

1 reference

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Growth differentiation factor 15

7 April 2020

main subject

obesity

0 references

1 reference

protein homodimerization activity

GOA release 2020-03-11

1 reference

Growth differentiation factor 15

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Yumei Xiong

1

1 reference

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7 April 2020

Kenneth Walker

2

1 reference

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7 April 2020

Xiaoshan Min

3

1 reference

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7 April 2020

Clarence Hale

4

1 reference

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7 April 2020

Renee Komorowski

6

1 reference

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7 April 2020

Jasmine Davda

8

1 reference

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7 April 2020

Noi Nuanmanee

9

1 reference

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7 April 2020

Silke Miller

13

1 reference

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7 April 2020

Murielle M Véniant

16

1 reference

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7 April 2020

author name string

Thanhvien Tran

5

1 reference

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7 April 2020

Jerry Yang

7

1 reference

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7 April 2020

Dao Kemp

10

1 reference

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7 April 2020

Xiaozhen Wang

11

1 reference

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7 April 2020

Hantao Liu

12

1 reference

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7 April 2020

Ki Jeong Lee

14

1 reference

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7 April 2020

Zhulun Wang

15

1 reference

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7 April 2020

language of work or name

English

0 references

publication date

1 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29046435%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

7 April 2020

published in

1 reference

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7 April 2020

volume

9

1 reference

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7 April 2020

issue

412

1 reference

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Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013

7 April 2020

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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

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Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family

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The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism.

21 January 2018

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Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets

21 January 2018

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TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator

21 January 2018

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The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract

21 January 2018

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Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

21 January 2018

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Concise review: growth differentiation factor 15 in pathology: a clinical role?

21 January 2018

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NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism

21 January 2018

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Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

21 January 2018

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An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2

21 January 2018

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Structure of the ternary signaling complex of a TGF-beta superfamily member

21 January 2018

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A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors

21 January 2018

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Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.

21 January 2018

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Integrated upper gastrointestinal response to food intake

21 January 2018

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Peripheral mechanisms in the control of appetite and related experimental therapies in obesity

21 January 2018

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Area postrema: chemoreceptor circumventricular organ of the medulla oblongata

21 January 2018

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21 January 2018

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21 January 2018

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Effect of Roux-en-Y gastric bypass on satiety and food likes: the role of genetics

21 January 2018

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Lesion of the area postrema/nucleus of the solitary tract (AP/NTS) attenuates the anorectic effects of amylin and calcitonin gene-related peptide (CGRP) in rats

21 January 2018

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Noradrenergic neurons of the area postrema mediate amylin's hypophagic action

21 January 2018

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The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer

21 January 2018

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Growth Differentiation Factor 15 as a Biomarker in Cardiovascular Disease

21 January 2018

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Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The Relationship between Insulin Resistance and the Cardiovascular Biomarker Growth Differentiation Factor-15 in Obese Patients

21 January 2018

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10.1126/SCITRANSLMED.AAN8732

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29046435%20AND%20SRC:MED&resulttype=core&format=json

release_3jetx55sjbc6xoz73mnov3vtbu

7 April 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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