Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent (Q47616751)

4 February 2018

title

Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent (English)

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4 February 2018

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Moore RC

1

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4 February 2018

Hope J

2

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4 February 2018

McBride PA

3

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4 February 2018

McConnell I

4

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4 February 2018

Selfridge J

5

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4 February 2018

Melton DW

6

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4 February 2018

Manson JC

7

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4 February 2018

language of work or name

English

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publication date

1 February 1998

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4 February 2018

published in

Nature Genetics

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4 February 2018

volume

18

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4 February 2018

issue

2

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4 February 2018

page(s)

118-125

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4 February 2018

https://scigraph.springernature.com/pub.10.1038/ng0298-118

exact match

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Distinct prion proteins in short and long scrapie incubation period mice

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Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice

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Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

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Mice devoid of PrP are resistant to scrapie

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

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Pathology and immunocytochemistry of a kuru brain

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GENETICAL CONTROL OF THE INCUBATION PERIOD IN MICE OF THE NEUROLOGICAL DISEASE, SCRAPIE

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Identification of a gene which controls the incubation period of some strains of scrapie agent in mice.

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7 January 2021

Linkage of prion protein and scrapie incubation time genes

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7 January 2021

Linkage of the scrapie-associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis

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7 January 2021

Analysis of linkage between scrapie incubation period and the prion protein gene in mice

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7 January 2021

The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

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7 January 2021

Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice

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7 January 2021

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

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Genetic control of amyloid plaque production and incubation period in scrapie-infected mice

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A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency

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Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

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Structure and polymorphism of the mouse prion protein gene

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7 January 2021

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.

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7 January 2021

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

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7 January 2021

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

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7 January 2021

Separation and properties of cellular and scrapie prion proteins

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Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy.

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7 January 2021

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Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier

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Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie

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7 January 2021

Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters

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7 January 2021

Transmission of bovine spongiform encephalopathy and scrapie to mice.

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7 January 2021

The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes

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7 January 2021

Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy

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7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

Identifiers

DOI

10.1038/NG0298-118

1 reference

4 February 2018

PubMed ID

9462739

1 reference

4 February 2018