Activation of cyclin D1 expression by the ERK5 cascade (Q47670094)

4 February 2018

title

Activation of cyclin D1 expression by the ERK5 cascade (English)

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4 February 2018

author

Sara Salinas

2

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4 February 2018

author name string

Roseann Mulloy

1

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4 February 2018

Alexandre Philips

3

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Robert A Hipskind

4

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language of work or name

English

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publication date

1 August 2003

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4 February 2018

published in

Oncogene

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volume

22

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issue

35

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page(s)

5387-5398

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4 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206839

exact match

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cites work

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ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

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Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

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Fos family members induce cell cycle entry by activating cyclin D1.

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Cyclin D1 and prognosis in human breast cancer

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NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

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Regulatory role of MEF2D in serum induction of the c-jun promoter

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Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

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Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

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Transcriptional activation of the cyclin D1 gene is mediated by multiple cis-elements, including SP1 sites and a cAMP-responsive element in vascular endothelial cells

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

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Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.

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Characterization of a candidate bcl-1 gene

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

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Specific protection against breast cancers by cyclin D1 ablation

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206839

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4 February 2018

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4 February 2018