Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population. (Q47698413)

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scientific article published in August 2003

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English	Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.	scientific article published in August 2003

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6 November 2019

Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population (English)

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6 November 2019

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6 November 2019

John W. Holloway

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6 November 2019

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B Beghé

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S Rorke

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6 November 2019

Q Peng

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6 November 2019

T P Keith

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J B Clough

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6 November 2019

S T Holgate

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6 November 2019

publication date

1 August 2003

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6 November 2019

Clinical & Experimental Allergy

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6 November 2019

33

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6 November 2019

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6 November 2019

1111-1117

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6 November 2019

The genetic basis of atopic asthma

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https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The IL-4 receptor: signaling mechanisms and biologic functions

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Linkage and allelic association of atopy and markers flanking the IL4-receptor gene.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

A new polymorphism in the 5' flanking region of the human interleukin (IL)-4 gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Distinct signal transduction processes by IL-4 and IL-13 and influences from the Q551R variant of the human IL-4 receptor alpha chain

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Comparison of three methods for single nucleotide polymorphism typing for DNA bank studies: sequence-specific oligonucleotide probe hybridisation, TaqMan liquid phase hybridisation, and microplate array diagonal gel electrophoresis (MADGE).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The gene encoding interleukin-13: a susceptibility locus for asthma and related traits

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Factor analysis of asthma and atopy traits shows 2 major components, one of which is linked to markers on chromosome 5q.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

A Second-Generation Association Study of the 5q31 Cytokine Gene Cluster and the Interleukin-4 Receptor in Asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Common polymorphisms in the coding part of the IL4-receptor gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Haplotypes of the 5' region of the IL-4 gene and SNPs in the intergene sequence between the IL-4 and IL-13 genes are associated with atopic asthma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Polymorphisms in the IL4, IL4RA, and FCERIB genes and asthma severity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.2003.01731.X

21 January 2018

Identifiers

10.1046/J.1365-2222.2003.01731.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12911786%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12911786%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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