Clinical studies of reversal of drug resistance based on glutathione (Q47785533)

5 February 2018

review article

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title

Clinical studies of reversal of drug resistance based on glutathione (English)

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5 February 2018

author name string

P Calvert

1

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5 February 2018

K S Yao

2

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5 February 2018

T C Hamilton

3

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5 February 2018

P J O'Dwyer

4

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5 February 2018

publication date

1 April 1998

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5 February 2018

Chemico-biological Interactions

published in

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5 February 2018

volume

111-112

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5 February 2018

page(s)

213-224

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5 February 2018

Selective modification of glutathione metabolism

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High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

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Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.

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Radiosensitization of hypoxic tumor cells by depletion of intracellular glutathione

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Reduction in cellular glutathione by buthionine sulfoximine and sensitization of murine tumor cells resistant to L-phenylalanine mustard.

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Dechlorination of L-phenylalanine mustard by sensitive and resistant tumor cells and its relationship to intracellular glutathione content.

7 January 2021

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Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

7 January 2021

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Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione

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The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines

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AP-1 function and regulation

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Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione

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Depletion of Glutathione in Normal and Malignant Human Cells In Vivo by Buthionine Sulfoximine: Clinical and Biochemical Results

7 January 2021

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Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz

7 January 2021

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Reduction in glutathione content of L-PAM resistant L1210 Cells confers drug sensitivity.

7 January 2021

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Comparison of nitrogen-mustard-sensitive and -resistant yoshida sarcomas

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Membrane transport, sulfhydryl levels and DNA cross-linking in Chinese hamster ovary cell mutants sensitive and resistant to melphalan.

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Cellular glutathione (GSH) and glutathione S-transferase (GST) activity in human ovarian tumor biopsies following exposure to alkylating agents

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-2797(98)00008-8

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5 February 2018

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5 February 2018