Interleukin-10 modulates susceptibility in experimental cerebral malaria. (Q47823424)

5 February 2018

title

Interleukin-10 modulates susceptibility in experimental cerebral malaria. (English)

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5 February 2018

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Kossodo S

1

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Monso C

2

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Juillard P

3

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Velu T

4

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Goldman M

5

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Grau GE

6

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publication date

1 August 1997

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published in

Immunology

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volume

91

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issue

4

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page(s)

536-540

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L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria.

cites work

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12 December 2020

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

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Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

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Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole.

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Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

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Tumor necrosis factor and disease severity in children with falciparum malaria.

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Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor

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Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria

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Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

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Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data

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Production of interferon-gamma during infection of mice with Plasmodium chabaudi chabaudi.

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Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.

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12 December 2020

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria.

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IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

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12 December 2020

IL-10 inhibits cytokine production by activated macrophages

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12 December 2020

Immune mechanisms in bacterial and parasitic diseases: protective immunity versus pathology.

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12 December 2020

A protective role for endogenous tumor necrosis factor in Toxoplasma gondii infection

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12 December 2020

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia

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12 December 2020

In vivo induction of interleukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: differential modulation by cyclosporin A

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12 December 2020

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation

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12 December 2020

Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent

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12 December 2020

Profiles of cytokine production in relation with susceptibility to cerebral malaria.

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12 December 2020

High levels of circulating IL-10 in human malaria.

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12 December 2020

Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes

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12 December 2020

TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction.

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12 December 2020

Antigen presentation by human dermal microvascular endothelial cells. Immunoregulatory effect of IFN-gamma and IL-10

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12 December 2020

Murine AIDS protects mice against experimental cerebral malaria: down-regulation by interleukin 10 of a T-helper type 1 CD4+ cell-mediated pathology

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12 December 2020

Immunocytochemical detection of cytokines in the lymph nodes and brains of mice resistant or susceptible to toxoplasmic encephalitis.

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12 December 2020

Elevated serum levels of IL-10 and IFN-gamma in patients with acute Plasmodium falciparum malaria.

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12 December 2020

Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections.

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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12 December 2020

10.1046/J.1365-2567.1997.00290.X

Identifiers

DOI

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5 February 2018

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5 February 2018