Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies. (Q47829675)

6 February 2018

title

Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies. (English)

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6 February 2018

Marga van de Vegte-Bolmer

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9

object named as

Marga van de Vegte-Bolmer

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Robert Sauerwein

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6 February 2018

Will Roeffen

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object named as

Will Roeffen

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6 February 2018

Hendrik Gerard Stunnenberg

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object named as

Hendrik G Stunnenberg

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6 February 2018

author name string

Nikolay Outchkourov

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6 February 2018

Adriaan Vermunt

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6 February 2018

Josephine Jansen

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6 February 2018

Anita Kaan

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6 February 2018

Karina Teelen

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6 February 2018

Edwin Lasonder

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Anneke Braks

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6 February 2018

Li Yan Qiu

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language of work or name

English

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publication date

9 April 2007

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6 February 2018

Journal of Biological Chemistry

published in

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volume

282

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page(s)

17148-17156

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issue

23

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6 February 2018

Malaria transmission-blocking vaccines--how can their development be supported?

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A central role for P48/45 in malaria parasite male gamete fertility

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Properties of epitopes of pfs 48/45, a target of transmission blocking monoclonal antibodies, on gametes of different isolates of plasmodium falciparum

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Immunological properties of recombinant proteins of the transmission blocking vaccine candidate, Pfs48/45, of the human malaria parasite Plasmodium falciparum produced in Escherichia coli.

21 January 2018

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Cloning and expression of the gene coding for the transmission blocking target antigen Pfs48/45 of Plasmodium falciparum.

21 January 2018

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Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry.

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Predicted disulfide-bonded structures for three uniquely related proteins of Plasmodium falciparum, Pfs230, Pfs48/45 and Pf12.

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Sequential expression of antigens on sexual stages of Plasmodium falciparum accessible to transmission-blocking antibodies in the mosquito

21 January 2018

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Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody

21 January 2018

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Sustained high-titer antibody responses induced by conjugating a malarial vaccine candidate to outer-membrane protein complex

21 January 2018

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Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25.

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Identifiers

DOI

10.1074/JBC.M700948200

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6 February 2018

PubMed ID

17426022

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6 February 2018