Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. (Q47838612)

6 February 2018

title

Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. (English)

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6 February 2018

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Hardeland U

1

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6 February 2018

Bentele M

series ordinal

2

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6 February 2018

Jiricny J

series ordinal

3

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6 February 2018

Schär P

series ordinal

4

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6 February 2018

language of work or name

English

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publication date

1 October 2000

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6 February 2018

Journal of Biological Chemistry

published in

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6 February 2018

volume

275

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issue

43

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6 February 2018

page(s)

33449-33456

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6 February 2018

Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues

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A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch

21 January 2018

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3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

21 January 2018

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5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

21 January 2018

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Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase.

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Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions

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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

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Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

21 January 2018

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Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

21 January 2018

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Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage

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DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005095200

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6 February 2018

PubMed ID

10938281

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6 February 2018