Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice. (Q47849462)

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English	Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.	scientific article

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scholarly article

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice. (English)

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Rho associated coiled-coil containing protein kinase 2

1 reference

GOA release 2020-03-11

negative regulation of nitric oxide biosynthetic process

1 reference

GOA release 2020-03-11

Rho-associated coiled-coil containing protein kinase 2

1 reference

GOA release 2020-03-11

Rho-associated coiled-coil containing protein kinase 1

1 reference

GOA release 2020-03-11

Nitric oxide synthase 3, endothelial cell

1 reference

GOA release 2020-03-11

10

object named as

James K Liao

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

2

object named as

Kensuke Noma

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

author name string

Yukio Hiroi

1

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Hyung-Hwan Kim

3

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Nikola Sladojevic

4

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Corey E Tabit

5

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Yuxin Li

6

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Guray Soydan

7

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Salvatore Salomone

8

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Michael A Moskowitz

9

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

publication date

19 January 2018

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Circulation Journal

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

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https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

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https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

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https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of Rho-kinase in the bovine brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection mediated by changes in the endothelial actin cytoskeleton.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elongation factor-1 alpha is a novel substrate of rho-associated kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct vascular effects of HMG-CoA reductase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbalanced expression of the different subunits of elongation factor 1 in diabetic skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoprenoids as mediators of the biological effects of statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute reduction of myocardial infarct size by a hydroxymethyl glutaryl coenzyme A reductase inhibitor is mediated by endothelial nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rocks: multifunctional kinases in cell behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Rho kinase activity in a Taiwanese population with metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased leukocyte ROCK activity in patients after acute ischemic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins inhibit Rho kinase activity in patients with atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a modified ROCK2 protein that allows use of N6-ATP analogs for the identification of novel substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective ROCK2 inhibition in focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29353861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1253/CIRCJ.CJ-17-0732

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

0 references

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/29353861

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