Patched1 is required in neural crest cells for the prevention of orofacial clefts (Q47898096)

6 February 2018

title

Patched1 is required in neural crest cells for the prevention of orofacial clefts (English)

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6 February 2018

author

Robert G. Parton

6

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6 February 2018

Carol Wicking

8

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6 February 2018

Vicki Metzis

object named as

Vicki Metzis

1

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author name string

Andrew D Courtney

2

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6 February 2018

Markus C Kerr

3

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6 February 2018

Charles Ferguson

4

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6 February 2018

Maria C Rondón Galeano

5

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6 February 2018

Brandon J Wainwright

7

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6 February 2018

publication date

29 July 2013

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6 February 2018

published in

Human Molecular Genetics

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6 February 2018

volume

22

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6 February 2018

issue

24

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6 February 2018

page(s)

5026-5035

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6 February 2018

Cleft lip and palate: understanding genetic and environmental influences

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Multiple nevoid basal-cell epithelioma, jaw cysts and bifid rib. A syndrome

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Contributions of PTCH gene variants to isolated cleft lip and palate

21 January 2018

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Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

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Patched acts catalytically to suppress the activity of Smoothened

21 January 2018

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

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Cilia and Hedgehog responsiveness in the mouse

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

21 January 2018

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Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

21 January 2018

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

21 January 2018

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Patched 1 conditional null allele in mice.

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Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

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Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse

21 January 2018

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Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates

21 January 2018

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Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

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A primary cilia-dependent etiology for midline facial disorders.

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Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape

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Novel skeletogenic patterning roles for the olfactory pit.

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Neural crest and ectodermal cells intermix in the nasal placode to give rise to GnRH-1 neurons, sensory neurons, and olfactory ensheathing cells

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FGF signaling regulates cytoskeletal remodeling during epithelial morphogenesis.

21 January 2018

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A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination

21 January 2018

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Emerging roles for p120-catenin in cell adhesion and cancer

21 January 2018

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Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia

21 January 2018

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Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

21 January 2018

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Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

21 January 2018

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21 January 2018

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Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome

21 January 2018

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Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.

21 January 2018

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A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm

21 January 2018

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Impaired FGF signaling contributes to cleft lip and palate

21 January 2018

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WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud.

21 January 2018

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Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape

21 January 2018

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Myosin II regulates complex cellular arrangement and epithelial architecture in Drosophila.

21 January 2018

1 reference

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Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

21 January 2018

1 reference

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Expression of members of the Fgf family and their receptors during midfacial development

21 January 2018

1 reference

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Mechanical signals trigger Myosin II redistribution and mesoderm invagination in Drosophila embryos

21 January 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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Genomic screen for genes involved in mammalian craniofacial development

21 January 2018

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SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT353

Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity

21 January 2018

1 reference

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Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies

21 January 2018

1 reference

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Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDT353

1 reference

6 February 2018

release_a6cuh57mtfelhgi44jwvnjmzwi

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a6cuh57mtfelhgi44jwvnjmzwi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

6 February 2018