Saxagliptin prevents vascular remodeling and oxidative stress in db/db mice. Role of endothelial nitric oxide synthase uncoupling and cyclooxygenase. (Q47903414)

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scientific article published on 6 October 2015

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English	Saxagliptin prevents vascular remodeling and oxidative stress in db/db mice. Role of endothelial nitric oxide synthase uncoupling and cyclooxygenase.	scientific article published on 6 October 2015

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scholarly article

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

Saxagliptin prevents vascular remodeling and oxidative stress in db/db mice. Role of endothelial nitric oxide synthase uncoupling and cyclooxygenase. (English)

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

microvasculature remodeling

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based on heuristic

inferred from title

5

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

object named as

Chiara Rossi

2

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object named as

Anna Solini

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author name string

Emiliano Duranti

3

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

Stefano Taddei

4

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

Agostino Virdis

6

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

publication date

6 October 2015

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

Vascular Pharmacology

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

76

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

62-71

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Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

Persistent remodeling of resistance arteries in type 2 diabetic patients on antihypertensive treatment.

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Endothelial dysfunction in small resistance arteries of patients with non-insulin-dependent diabetes mellitus

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Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling

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Endothelium-mediated control of vascular tone: COX-1 and COX-2 products

1 reference

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7 January 2021

Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins

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The assessment of endothelial function: from research into clinical practice

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Prognostic significance of small-artery structure in hypertension.

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Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

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The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity

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Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries.

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Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition

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Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors.

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Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats.

1 reference

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7 January 2021

Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats.

1 reference

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7 January 2021

Cyclooxygenase-2 inhibition improves vascular endothelial dysfunction in a rat model of endotoxic shock: role of inducible nitric-oxide synthase and oxidative stress.

1 reference

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7 January 2021

Cyclooxygenase-1 Is Involved in Endothelial Dysfunction of Mesenteric Small Arteries From Angiotensin II–Infused Mice

1 reference

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7 January 2021

Resistance artery mechanics and composition in angiotensin II-infused mice: effects of cyclooxygenase-1 inhibition

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7 January 2021

KR-62436, 6-{2-[2-(5-cyano-4,5-dihydropyrazol-1-yl)-2-oxoethylamino]ethylamino}nicotinonitrile, is a novel dipeptidyl peptidase-IV (DPP-IV) inhibitor with anti-hyperglycemic activity

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7 January 2021

Vascular generation of tumor necrosis factor-α reduces nitric oxide availability in small arteries from visceral fat of obese patients

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7 January 2021

Enhanced vascular reactivity of small mesenteric arteries from diabetic mice is associated with enhanced oxidative stress and cyclooxygenase products

1 reference

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7 January 2021

Resistance artery mechanics and composition in angiotensin II-infused rats: effects of aldosterone antagonism

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7 January 2021

Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries

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Pressure-independent cerebrovascular remodelling and changes in myogenic reactivity in diabetic Goto-Kakizaki rat in response to glycaemic control

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Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control

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Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

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Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways

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Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride

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7 January 2021

Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.

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Role of advanced glycation end products with oxidative stress in resistance artery dysfunction in type 2 diabetic mice

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Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress.

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7 January 2021

Endothelial nitric oxide synthase in vascular disease: from marvel to menace

1 reference

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7 January 2021

Is oxidative stress a therapeutic target in cardiovascular disease?

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7 January 2021

Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome

1 reference

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7 January 2021

Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice

1 reference

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Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids

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The dipeptidyl peptidase-4 inhibitor linagliptin attenuates inflammation and accelerates epithelialization in wounds of diabetic ob/ob mice

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The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA.

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Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.

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7 January 2021

Identifiers

10.1016/J.VPH.2015.10.002

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/26455387

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