TCF: transcriptional activator or repressor? (Q47926649)

6 February 2018

review article

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title

TCF: transcriptional activator or repressor? (English)

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6 February 2018

author name string

Bienz M

series ordinal

1

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6 February 2018

publication date

1 June 1998

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6 February 2018

Current Opinion in Cell Biology

published in

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6 February 2018

volume

10

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6 February 2018

issue

3

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6 February 2018

page(s)

366-372

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6 February 2018

Functional interaction of beta-catenin with the transcription factor LEF-1

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LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

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A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer

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LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

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dishevelled and armadillo act in the wingless signalling pathway in Drosophila

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Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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A versatile transcriptional effector of Wingless signaling

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TCF/LEF factor earn their wings

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

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An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling

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Endoderm induction in Drosophila: the nuclear targets of the inducing signals

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A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

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Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis.

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LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter

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Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

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Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

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Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos

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Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis

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HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

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7 January 2021

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

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7 January 2021

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

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Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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Distinct roles for P-CREB and LEF-1 in TCR alpha enhancer assembly and activation on chromatin templates in vitro

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A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction

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An HMG-box-containing T-cell factor required for thymocyte differentiation.

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

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7 January 2021

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

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7 January 2021

An HMG I/Y-containing repressor complex and supercoiled DNA topology are critical for long-range enhancer-dependent transcription in vitro

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ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

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7 January 2021

The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin.

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7 January 2021

Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway

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7 January 2021

Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus

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7 January 2021

Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

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7 January 2021

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

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7 January 2021

Two different thresholds of wingless signalling with distinct developmental consequences in the Drosophila midgut

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7 January 2021

The reprogramming of transcriptional competence

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7 January 2021

An enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymus

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7 January 2021

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Identifiers

DOI

1 reference

6 February 2018

PubMed ID

9640538

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6 February 2018