Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. (Q47954457)

7 February 2018

title

Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. (English)

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7 February 2018

main subject

sb-202190

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ChEBI release 2020-05-28

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S Nemoto

1

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7 February 2018

J Xiang

series ordinal

2

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7 February 2018

S Huang

series ordinal

3

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7 February 2018

A Lin

series ordinal

4

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7 February 2018

language of work or name

English

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publication date

1 June 1998

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7 February 2018

Journal of Biological Chemistry

published in

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7 February 2018

volume

273

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7 February 2018

issue

26

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7 February 2018

page(s)

16415-16420

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7 February 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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Errors of homeostasis and deregulated apoptosis

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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Apoptosis by death factor

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Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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Inhibition of Bax channel-forming activity by Bcl-2

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Channel formation by antiapoptotic protein Bcl-2.

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Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

21 January 2018

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The primary structure of p38 gamma: a new member of p38 group of MAP kinases

21 January 2018

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SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

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Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

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Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

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Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

21 January 2018

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

21 January 2018

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A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

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The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation.

21 January 2018

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Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

21 January 2018

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The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

21 January 2018

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

21 January 2018

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Osmotic regulation of cytokine synthesis in vitro

21 January 2018

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BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

21 January 2018

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Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors

21 January 2018

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Involvement of an ICE-like protease in Fas-mediated apoptosis

21 January 2018

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Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

21 January 2018

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Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

21 January 2018

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Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

21 January 2018

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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

21 January 2018

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Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.26.16415

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways

21 January 2018

1 reference

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MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.26.16415

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.26.16415

1 reference

7 February 2018

PubMed ID

9632706

1 reference

7 February 2018