SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity (Q47973753)

7 February 2018

title

SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity (English)

1 reference

7 February 2018

1 reference

Alik Demishtein

1

1 reference

7 February 2018

Milana Fraiberg

2

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7 February 2018

Dikla Berko

3

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7 February 2018

Boaz Tirosh

4

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7 February 2018

Zvulun Elazar

5

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7 February 2018

Ami Navon

6

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7 February 2018

publication date

9 August 2017

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7 February 2018

published in

Autophagy

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7 February 2018

volume

13

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7 February 2018

issue

10

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7 February 2018

page(s)

1697-1708

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7 February 2018

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.

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A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells

26 August 2018

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Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

26 August 2018

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Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice

26 August 2018

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Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway

26 August 2018

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Inherent asymmetry in the 26S proteasome is defined by the ubiquitin receptor RPN13

26 August 2018

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A novel crosstalk between two major protein degradation systems: regulation of proteasomal activity by autophagy.

26 August 2018

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The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

26 August 2018

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Failure of amino acid homeostasis causes cell death following proteasome inhibition.

26 August 2018

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Ubiquitination and selective autophagy

26 August 2018

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Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program

26 August 2018

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Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

26 August 2018

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Biogenesis and cargo selectivity of autophagosomes

26 August 2018

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A new autophagy-related checkpoint in the degradation of an ERAD-M target

26 August 2018

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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

26 August 2018

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Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

26 August 2018

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Getting to first base in proteasome assembly

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

26 August 2018

1 reference

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

26 August 2018

1 reference

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Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

26 August 2018

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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

26 August 2018

1 reference

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The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.

26 August 2018

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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

26 August 2018

1 reference

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Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Proteasome subunit Rpn13 is a novel ubiquitin receptor

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Single-cell phospho-protein analysis by flow cytometry

26 August 2018

1 reference

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

26 August 2018

1 reference

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Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

26 August 2018

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Autophagy is activated for cell survival after endoplasmic reticulum stress

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Progressively impaired proteasomal capacity during terminal plasma cell differentiation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

β-catenin is a target for the ubiquitin–proteasome pathway

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

A 26 S protease subunit that binds ubiquitin conjugates

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Post-translational regulation of IgM expression in B lymphocytes. Selective nonlysosomal degradation of assembled secretory IgM is temperature-dependent and occurs prior to the trans-Golgi

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Polymerization of secretory IgM in B lymphocytes is prevented by a prior targeting to a degradation pathway

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640208

Autophagy: links with the proteasome

26 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F15548627.2017.1356549

10.1080/15548627.2017.1356549

21 January 2018

Identifiers

DOI

1 reference

7 February 2018

PMC publication ID

5640208

0 references

1 reference

7 February 2018